A molecular subtype of glioblastoma characterized by lack of p53 mutations, chromosome 7 amplifications or deletions, and high levels of EGFR amplification.
Comprehensive, easy-to-understand information about this condition
How we create this content →The documentation surrounding classical glioblastoma is limited due to the rarity of this specific subtype and the complexity of glioblastomas as a whole. Systematic clinical studies have been constrained by the aggressive nature of the disease and the challenges in obtaining sufficient patient samples. As research continues, we hope to gain a clearer understanding of its characteristics and treatment options.
To navigate classical glioblastoma, consider seeking a neuro-oncologist with expertise in brain tumors, particularly glioblastomas. They can provide tailored treatment options based on the latest research. You can also explore clinical trials for potential new therapies; the ClinicalTrials.gov website is a valuable resource for this. Although there are currently no identified patient organizations for classical glioblastoma, you may find support through general brain cancer organizations. Genetic counseling may also be beneficial, especially if you have concerns about familial risk factors.
There are several orphan drugs currently designated for classical glioblastoma, including (1-hydroxy-2-oxopiperidin-3-yl)phosphonic acid and anti-beta1 integrin monoclonal antibody. Additionally, there are 5 active clinical trials investigating various treatment approaches. For more information on these trials, you can visit ClinicalTrials.gov and search for classical glioblastoma: https://clinicaltrials.gov/search?cond=classical%20glioblastoma. This ongoing research represents hope for better management strategies in the future.
Actionable guidance for navigating care for classical glioblastoma
To navigate classical glioblastoma, consider seeking a neuro-oncologist with expertise in brain tumors, particularly glioblastomas. They can provide tailored treatment options based on the latest research. You can also explore clinical trials for potential new therapies; the ClinicalTrials.gov website is a valuable resource for this. Although there are currently no identified patient organizations for classical glioblastoma, you may find support through general brain cancer organizations. Genetic counseling may also be beneficial, especially if you have concerns about familial risk factors.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The documentation surrounding classical glioblastoma is limited due to the rarity of this specific subtype and the complexity of glioblastomas as a whole. Systematic clinical studies have been constrained by the aggressive nature of the disease and the challenges in obtaining sufficient patient samples. As research continues, we hope to gain a clearer understanding of its characteristics and treatment options.
To navigate classical glioblastoma, consider seeking a neuro-oncologist with expertise in brain tumors, particularly glioblastomas. They can provide tailored treatment options based on the latest research. You can also explore clinical trials for potential new therapies; the ClinicalTrials.gov website is a valuable resource for this. Although there are currently no identified patient organizations for classical glioblastoma, you may find support through general brain cancer organizations. Genetic counseling may also be beneficial, especially if you have concerns about familial risk factors.
There are several orphan drugs currently designated for classical glioblastoma, including (1-hydroxy-2-oxopiperidin-3-yl)phosphonic acid and anti-beta1 integrin monoclonal antibody. Additionally, there are 5 active clinical trials investigating various treatment approaches. For more information on these trials, you can visit ClinicalTrials.gov and search for classical glioblastoma: https://clinicaltrials.gov/search?cond=classical%20glioblastoma. This ongoing research represents hope for better management strategies in the future.
Actionable guidance for navigating care for classical glioblastoma
To navigate classical glioblastoma, consider seeking a neuro-oncologist with expertise in brain tumors, particularly glioblastomas. They can provide tailored treatment options based on the latest research. You can also explore clinical trials for potential new therapies; the ClinicalTrials.gov website is a valuable resource for this. Although there are currently no identified patient organizations for classical glioblastoma, you may find support through general brain cancer organizations. Genetic counseling may also be beneficial, especially if you have concerns about familial risk factors.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The documentation surrounding classical glioblastoma is limited due to the rarity of this specific subtype and the complexity of glioblastomas as a whole. Systematic clinical studies have been constrained by the aggressive nature of the disease and the challenges in obtaining sufficient patient samples. As research continues, we hope to gain a clearer understanding of its characteristics and treatment options.
To navigate classical glioblastoma, consider seeking a neuro-oncologist with expertise in brain tumors, particularly glioblastomas. They can provide tailored treatment options based on the latest research. You can also explore clinical trials for potential new therapies; the ClinicalTrials.gov website is a valuable resource for this. Although there are currently no identified patient organizations for classical glioblastoma, you may find support through general brain cancer organizations. Genetic counseling may also be beneficial, especially if you have concerns about familial risk factors.
There are several orphan drugs currently designated for classical glioblastoma, including (1-hydroxy-2-oxopiperidin-3-yl)phosphonic acid and anti-beta1 integrin monoclonal antibody. Additionally, there are 5 active clinical trials investigating various treatment approaches. For more information on these trials, you can visit ClinicalTrials.gov and search for classical glioblastoma: https://clinicaltrials.gov/search?cond=classical%20glioblastoma. This ongoing research represents hope for better management strategies in the future.
Actionable guidance for navigating care for classical glioblastoma
To navigate classical glioblastoma, consider seeking a neuro-oncologist with expertise in brain tumors, particularly glioblastomas. They can provide tailored treatment options based on the latest research. You can also explore clinical trials for potential new therapies; the ClinicalTrials.gov website is a valuable resource for this. Although there are currently no identified patient organizations for classical glioblastoma, you may find support through general brain cancer organizations. Genetic counseling may also be beneficial, especially if you have concerns about familial risk factors.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Consider asking your healthcare providers these condition-specific questions
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.