1. Acceptance of Terms
By accessing or using Kisho at kishomed.io ("the Service", "the Platform"), operated by Kisho ("we", "us", "our"), you agree to be bound by these Terms of Service ("Terms"). If you do not agree to these Terms, you must not access or use the Service. These Terms apply to all visitors, users, subscribers, and organizations accessing the Platform.
2. Description of Service
Kisho is a rare disease intelligence platform that aggregates, synthesizes, and delivers information from 12+ authoritative data sources across 10,888+ diseases. The Service includes, but is not limited to:
- AI-generated disease intelligence reports synthesized from authoritative biomedical databases
- Saved Search and Change Feed for cross-domain disease monitoring (news, clinical trials, publications, policy, FDA activity)
- News intelligence curated from 25+ sources with AI categorization and disease tagging
- 50-state policy and legislation tracking with AI classification
- Clinical trial tracking with status monitoring and alert notifications
- Company and competitive intelligence profiles with event tracking
- Publications landscape analysis with research-type classification
- Grant and funding landscape analysis with cross-domain gap detection
- Embeddable disease information widgets for third-party websites
- Workspace with AI-powered editing tools (Validate, Simplify, Elaborate, Cite)
- B2B API for programmatic access to disease intelligence data
- WordPress publishing integration for content distribution
- Patient Advocacy Group (PAG) directory and organizational tools
- Free public tools including clinical trial explorer, publications explorer, grants explorer, and report writer demo
3. Subscription Tiers and Billing
Kisho offers multiple subscription tiers. All tiers are available to all user types, including individuals, organizations, and companies:
3.1 Subscription Plans
- Free: $0 per month. Includes core disease information, limited follows and monitoring, and access to free public tools.
- Professional: $199 per month ($1,999 per year billed annually). Organizational tier with workspace access, co-branded embeds, real-time alerts, and full AI report generation.
- Enterprise: Starting at $50,000 per year (custom pricing). Full platform access with white-label options, API access, custom data feeds, and dedicated support.
3.2 Nonprofit and Academic Pricing
Discounted pricing is available for verified 501(c)(3) nonprofits, academic institutions, and patient advocacy organizations. Eligibility is determined during checkout and may require verification. Nonprofit pricing does not change your subscription tier or feature access; it applies a discount to the standard tier pricing.
3.3 Free Trials
Professional plans may include a 14-day free trial. You will not be charged during the trial period. If you do not cancel before the trial ends, your subscription will automatically convert to a paid plan and you will be billed at the applicable rate. You may cancel your trial at any time before it expires.
3.4 Billing and Cancellation
All payments are processed through Stripe. Subscriptions renew automatically on a monthly or annual basis depending on the plan you selected. You may cancel your subscription at any time through your account settings. Upon cancellation, you will retain access to your paid tier features until the end of your current billing period, after which your account will revert to the Free tier. We do not offer prorated refunds for partial billing periods.
4. User Accounts
To access certain features of the Service, you must create an account. By creating an account, you agree to:
- Provide accurate, current, and complete information during registration
- Maintain the security and confidentiality of your account credentials
- Promptly update your account information if it changes
- Accept responsibility for all activities that occur under your account
- Notify us immediately of any unauthorized use of your account
You may not share your account credentials with others or allow multiple individuals to use a single account. Workspace team member seats are provided for authorized multi-user access within your subscription tier limits.
5. AI-Generated Content
Kisho uses artificial intelligence to generate disease reports, news summaries, policy briefings, intelligence signals, and other content. AI-generated content is derived from authoritative biomedical data sources and is fact-checked against source data. However, AI-generated content may contain errors, omissions, or inaccuracies. You should independently verify any information before relying on it.
5.1 Disease Intelligence Reports
AI-generated disease reports are synthesized from multiple databases including MONDO, OMIM, Orphanet, HPO, ClinicalTrials.gov, FDA, PubMed, ClinVar, ClinGen, GeneReviews, HGNC, and Congress.gov. Reports undergo automated fact-checking and quality review, but they are not reviewed by human medical professionals before publication. Reports may not reflect the most recent research or clinical developments.
5.2 AI Editing Tools
Workspace AI editing tools (Validate, Simplify, Elaborate, and Cite) process user-highlighted text through AI models to provide validation assessments, simplified language, expanded content, and citation suggestions. The output of these tools is AI-generated and should be reviewed for accuracy before use. The Validate tool provides confidence scores that represent the AI model's assessment, not a definitive determination of accuracy.
5.3 News and Policy Intelligence
News articles are curated from third-party sources and may be categorized, summarized, or tagged by AI systems. Policy tracking content reflects AI classification of legislative activity. We do not guarantee the completeness, timeliness, or accuracy of AI-processed news or policy content.
6. Medical Disclaimer
The information provided through Kisho, including AI-generated disease reports, clinical trial data, publication summaries, drug information, and all other content, is for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. Information about drugs, treatments, clinical trials, or genetic variants should not be used to make medical decisions without consulting a qualified healthcare provider. Drug market status information (including withdrawn or discontinued designations) is provided for awareness purposes and should be confirmed with authoritative regulatory sources. Always seek the advice of your physician or other qualified health professional with any questions you may have regarding a medical condition.
7. PAG Registration and Organization Accounts
Patient Advocacy Groups and other organizations registering on Kisho agree to:
- Provide accurate organizational information including legal name, type, and contact details
- Represent a legitimate patient advocacy, research, or healthcare organization
- Undergo our verification process for disease claims and organizational status
- Keep organization information current and accurate
- Comply with applicable tier limits on team members, embeds, and disease claims
- Use organizational features (workspace, embeds, API access) only for authorized purposes
We reserve the right to revoke verification status or restrict organizational features if we determine that the information provided is inaccurate or the organization does not meet our eligibility criteria.
8. Embeddable Widgets
Kisho provides embeddable disease information widgets for use on third-party websites, subject to your subscription tier limits.
- All embeds must display "Powered by Kisho" attribution unless you hold an Enterprise subscription with white-label rights.
- Embedding Kisho content on your website does not transfer any intellectual property rights to you.
- You may not modify, reverse-engineer, or extract the underlying code or data from embedded widgets.
- We reserve the right to disable embeds that are used on sites that violate these Terms or that contain harmful, misleading, or objectionable content.
- Embed availability, styling, and content are subject to change. We will make reasonable efforts to maintain backward compatibility.
9. B2B API Access
Programmatic access to Kisho data is available through our REST API. API access is included in all subscription plans, with rate limits determined by your plan tier.
- API keys are confidential. Keys are cryptographically hashed in our database and cannot be recovered if lost. You are responsible for safeguarding your API keys.
- Rate limits apply to all API access (up to 1,000 requests per hour per key for tenant endpoints). Exceeding rate limits may result in temporary or permanent restriction of access.
- Data obtained through the API may not be redistributed, resold, sublicensed, or made available to third parties without a separate data licensing agreement.
- API access is provided for integration with your own products and internal systems. Building a competing service using Kisho API data is prohibited.
- We may modify API endpoints, response formats, or rate limits with reasonable advance notice.
- WordPress API keys (prefixed
kisho_wp_) are limited to WordPress publishing integration use.
10. User Contributions
When contributing content to Kisho, including workspace reports, comments, feedback, or other user-submitted content, you agree that:
- Your contributions are accurate and based on reliable sources to the best of your knowledge
- You will not submit content that is misleading, harmful, defamatory, or inappropriate
- Your contributions may be reviewed and moderated by our team and AI systems
- You grant Kisho a non-exclusive, worldwide, royalty-free license to use, display, reproduce, and distribute your contributions in connection with the Service
- You retain ownership of your original contributions, but acknowledge that Kisho may use them to improve the Service
11. Data Sources and Attribution
Kisho aggregates and synthesizes data from the following authoritative sources, among others:
- MONDO Disease Ontology — disease classification and identifiers
- OMIM (Online Mendelian Inheritance in Man) — genetic disease data
- Orphanet — rare disease epidemiology and nomenclature
- HPO (Human Phenotype Ontology) — clinical phenotype descriptions
- ClinicalTrials.gov — clinical trial registrations and status
- FDA / openFDA — drug approvals, orphan designations, and market status
- PubMed / NCBI — biomedical literature
- ClinVar — variant-disease clinical significance
- ClinGen — gene-disease validity classifications
- GeneReviews — expert-authored clinical reviews (copyright University of Washington)
- HGNC — gene nomenclature and chromosome locations
- Congress.gov / state legislatures — legislative activity
Each data source is subject to its own license terms. Kisho content is a derivative synthesis of these sources. You must not misattribute Kisho-generated content as original research, primary data, or as originating from any upstream data source. When referencing Kisho content in publications or reports, it should be attributed to Kisho (kishomed.io).
12. Intellectual Property
The Service, including its design, software, AI models, generated reports, analytics, branding, and documentation (excluding user contributions and upstream data source content) is owned by Kisho and protected by intellectual property laws.
- You may not copy, modify, distribute, sell, or lease any part of the Service without our written consent.
- AI-generated reports provided to you under a paid subscription may be used within your organization and shared with your stakeholders, but may not be resold or commercially redistributed as a standalone product.
- Enterprise subscribers with white-label agreements have additional usage rights as specified in their service agreement.
- Kisho's name, logo, and branding are trademarks and may not be used without permission.
13. Prohibited Conduct
You agree not to:
- Use the Service for any unlawful purpose or in violation of any applicable laws
- Submit false, misleading, or deliberately harmful information
- Impersonate others or misrepresent your affiliation with any person or organization
- Attempt to gain unauthorized access to our systems, accounts, or data
- Interfere with, disrupt, or overload the Service or its infrastructure
- Scrape, crawl, or collect data from the Service by automated means without an active API subscription or written permission
- Use the Service to build a competing product or service
- Circumvent subscription tier limits, rate limits, or access controls
- Remove, obscure, or alter "Powered by Kisho" attribution on embedded widgets
- Share, publish, or expose API keys or other access credentials
- Use AI-generated content from the Service to train machine learning models without our written consent
- Misrepresent Kisho content as original research, clinical data, or peer-reviewed publications
14. Privacy and Data
Your use of the Service is also governed by our Privacy Policy. By using the Service, you consent to the collection and use of information as described in the Privacy Policy. Workspace content, saved searches, and organizational data are stored securely and are not shared with other users or organizations unless you explicitly configure sharing settings. We may use aggregated, anonymized usage data to improve the Service.
15. Limitation of Liability
To the maximum extent permitted by applicable law, the Service is provided "as is" and "as available" without warranties of any kind, whether express or implied, including but not limited to implied warranties of merchantability, fitness for a particular purpose, and non-infringement.
We do not warrant that:
- The Service will be uninterrupted, timely, secure, or error-free
- AI-generated content will be accurate, complete, or current
- Data from third-party sources will be available or accurate
- The Service will meet your specific requirements
In no event shall Kisho, its officers, directors, employees, or agents be liable for any indirect, incidental, special, consequential, or punitive damages, including but not limited to loss of profits, data, use, or goodwill, arising out of or in connection with your use of the Service, whether based on warranty, contract, tort, or any other legal theory, and whether or not we have been advised of the possibility of such damages. Our total liability for any claim arising from these Terms or your use of the Service shall not exceed the amount you paid us in the twelve (12) months preceding the claim.
16. Indemnification
You agree to indemnify, defend, and hold harmless Kisho and its officers, directors, employees, and agents from and against any claims, liabilities, damages, losses, and expenses, including reasonable legal fees, arising out of or in any way connected with your access to or use of the Service, your violation of these Terms, your violation of any third-party rights, or any content you contribute to the Service.
17. Termination
We reserve the right to suspend or terminate your access to the Service at any time, with or without notice, for conduct that we believe violates these Terms, is harmful to other users or the Service, or for any other reason at our reasonable discretion.
Upon termination, your right to use the Service will immediately cease. If you have an active paid subscription, termination for cause will not entitle you to a refund. You may request export of your workspace data for up to 30 days following account termination by contacting us. Provisions of these Terms that by their nature should survive termination shall survive, including ownership, warranty disclaimers, indemnification, and limitations of liability.
18. Changes to Terms
We may modify these Terms at any time by posting the updated version on this page with a revised "Last updated" date. For material changes that affect your rights or obligations, we will provide notice via email or through the Service at least 30 days before the changes take effect. Your continued use of the Service after the effective date of any changes constitutes your acceptance of the modified Terms. If you do not agree to the modified Terms, you must stop using the Service and cancel any active subscription.
19. Governing Law and Disputes
These Terms shall be governed by and construed in accordance with the laws of the United States and the state in which Kisho is incorporated, without regard to conflict of law provisions. Any disputes arising from or relating to these Terms or the Service shall be resolved through binding arbitration in accordance with standard commercial arbitration rules, except that either party may seek injunctive or other equitable relief in any court of competent jurisdiction. You agree to waive any right to a jury trial or to participate in a class action.
20. Miscellaneous
- Entire Agreement: These Terms, together with our Privacy Policy, constitute the entire agreement between you and Kisho regarding the Service.
- Severability: If any provision of these Terms is found to be unenforceable, the remaining provisions will continue in full force and effect.
- Waiver: Our failure to enforce any provision of these Terms shall not constitute a waiver of that provision or any other provision.
- Assignment: You may not assign or transfer your rights under these Terms without our prior written consent. We may assign our rights and obligations without restriction.
- Force Majeure: We shall not be liable for any failure or delay in performance due to circumstances beyond our reasonable control, including natural disasters, pandemics, government actions, or interruption of third-party data sources.
