Ackerman syndrome

Ackerman syndrome is a rare condition that is mainly characterized by abnormal dental features, including pyramidal molar roots and taurodontism. In some families, these dental abnormalities have been seen across multiple generations. The condition may also be associated with a range of other features, making it a complex syndrome. Other features noted in people with this condition include an abnormal upper lip with a thickened, wide philtrum, hypotrichosis (reduced body hair), and eye issues such as juvenile glaucoma and entropion of the eyelid. In addition, differences in the hands, such as syndactyly (fusion of fingers) and clinodactyly (curved fifth fingers), have been observed. This range of findings highlights the variability in how the condition may present among affected individuals.

Common signs of Ackerman syndrome include dental abnormalities such as pyramidal molar roots and taurodontism. Some people with the condition may also show additional features like an abnormal upper lip, a thick and wide philtrum, and hypotrichosis. Other symptoms that have been reported include juvenile glaucoma, entropion of the eyelid, and hand differences such as syndactyly and clinodactyly of the fifth fingers.

Ackerman syndrome has been reported in a family across two generations, suggesting that genetics may play a role in the condition. No specific gene mutations have yet been identified, and known genetic causes have not been established. This suggests that while the condition appears to run in families, the exact genetic reasons remain unclear.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.