Cogan syndrome

Cogan syndrome is a rare autoimmune disorder of unknown origin. It is mainly known for causing inflammation in the eyes, most often affecting the cornea (a condition called interstitial keratitis), and for problems with balance and hearing including sudden hearing loss, ringing in the ears, and dizziness. In many cases, people with Cogan syndrome experience symptoms beyond the eyes and ears. Over 70% of cases may have signs of the condition affecting other parts of the body, making its overall impact variable. A negative test for syphilis is usually part of the evaluation process to help support the diagnosis.

Common symptoms include inflammation in the eye (interstitial keratitis), sudden hearing loss, ringing in the ears (tinnitus), and vertigo (a spinning sensation). These symptoms often appear together in people with Cogan syndrome.

Cogan syndrome is an autoimmune condition, but its exact cause is unknown. Information about genetic factors or other risk factors is currently limited for this condition.

Information about treatment is currently limited for this condition.

The outlook for people with Cogan syndrome can vary. Some may develop systemic effects that involve other organs, and the course of the condition may differ between individuals.

Information about current research and future directions is currently limited for this condition.