Rieger anomaly

Rieger anomaly is a congenital eye condition that involves abnormal development of the front parts of the eye. This condition is marked by distinct structural changes, including irregularities in the iris, which is the colored part of the eye, and deformities in the anterior chamber where fluid is housed. The defect is part of a spectrum of conditions related to anterior segment dysgenesis. It is also associated with features seen in Axenfeld anomaly, another ocular condition. This summary is based on the definition and descriptions provided by trusted sources.

People with Rieger anomaly may experience several distinctive eye changes. These include a severe deformity of the anterior chamber along with prominent strands in the eye structure. There is also marked atrophy, or thinning, of the iris stroma. In many cases, a hole or pseudo-hole formation occurs in the iris, and the pupil may not be in its normal central position (corectopia).

Rieger anomaly is a congenital defect, meaning it is present from birth. It is caused by abnormal eye development, specifically anterior segment dysgenesis. Information about any specific genetic changes or additional risk factors is not available in the provided sources.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.