Adams-Oliver syndrome 1

Adams-Oliver syndrome 1 is a rare genetic condition caused by a mutation in the ARHGAP31 gene. This condition is recognized by its association with defects affecting the scalp and limbs. The definition specifies that any Adams-Oliver syndrome in which the cause is a mutation in the ARHGAP31 gene is classified as this type. The available information mainly focuses on the genetic cause of the syndrome, and it has been associated with terms that reference scalp defects, limb abnormalities, and other congenital differences. Although multiple synonyms exist for this condition, the core concept remains that changes in the ARHGAP31 gene lead to its distinctive features.

People with Adams-Oliver syndrome 1 may show differences in the development of the scalp and limbs. Some descriptions of the condition refer to terms such as aplasia cutis congenita and limb reduction anomalies. However, detailed information regarding the full range of symptoms and how they vary among individuals is limited.

Adams-Oliver syndrome 1 is caused by a mutation in the ARHGAP31 gene. This genetic change affects normal development and is the key factor in the condition. The genetic basis of the syndrome is well noted in the medical definition.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.