Charcot-Marie-tooth disease, axonal, type 2JJ | Kisho | Kisho

Charcot-Marie-tooth disease, axonal, type 2JJ

Rare Disease

MONDO:0976227

Genes

Clinical Trials

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Patient Groups

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Patient-Friendly Information

Comprehensive, easy-to-understand information about this condition

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Last reviewed: Feb 2026

Evidence base: Developing

This report reflects available clinical information. Some areas may remain under active research.(4 data sources · Data coverage: Moderate)

Overview

Charcot-Marie-tooth disease, axonal, type 2JJ is a rare inherited condition that affects the peripheral nerves. Information about the detailed definition is currently limited, but this form of the disease is recognized as one of many types of Charcot-Marie-tooth disorders, which typically impact nerve function and muscle strength. This condition has been linked with changes in the BAG3 gene, suggesting a genetic contribution. The OMIM database lists this condition under OMIM:621095, highlighting its genetic background and its place among related inherited neuropathies.

Symptoms & Signs

Information about symptoms is currently limited for this condition.

Causes & Risk Factors

Genetic factors play a role in Charcot-Marie-tooth disease, axonal, type 2JJ. The condition has been associated with changes in the BAG3 gene. As an inherited disorder, the risk is linked to variations passed through family genes. Further details on the cause are currently limited.

Treatment & Management

Information about treatment is currently limited for this condition.

Prognosis & Outlook

Information about prognosis is currently limited for this condition.

Research & Clinical Trials

Information about research is currently limited for this condition.

Quick Resources

Helpful links for rare disease information and support

GARD (Genetic and Rare Diseases Information Center)NORD (National Organization for Rare Disorders)Find a Genetic Counselor

General Questions to Consider

Questions that may be helpful when speaking with your healthcare team

•Are there specialists or centers of excellence with experience in this condition?
•Is there a patient registry I could participate in?
•Should my family members consider genetic testing?
•What clinical trials might be available for this condition?
•Are there patient advocacy groups I should connect with?

This report reflects available clinical information. Some areas may remain under active research.(4 data sources · Data coverage: Moderate)

Overview

Symptoms & Signs

Information about symptoms is currently limited for this condition.

Causes & Risk Factors

Treatment & Management

Information about treatment is currently limited for this condition.

Prognosis & Outlook

Information about prognosis is currently limited for this condition.

Research & Clinical Trials

Information about research is currently limited for this condition.

Quick Resources

Helpful links for rare disease information and support

GARD (Genetic and Rare Diseases Information Center)NORD (National Organization for Rare Disorders)Find a Genetic Counselor

General Questions to Consider

Questions that may be helpful when speaking with your healthcare team

•Are there specialists or centers of excellence with experience in this condition?
•Is there a patient registry I could participate in?
•Should my family members consider genetic testing?
•What clinical trials might be available for this condition?
•Are there patient advocacy groups I should connect with?

Overview

This report reflects available clinical information. Some areas may remain under active research.(4 data sources · Data coverage: Moderate)

Overview

Symptoms & Signs

Information about symptoms is currently limited for this condition.

Causes & Risk Factors

Treatment & Management

Information about treatment is currently limited for this condition.

Prognosis & Outlook

Information about prognosis is currently limited for this condition.

Research & Clinical Trials

Information about research is currently limited for this condition.

Quick Resources

Helpful links for rare disease information and support

GARD (Genetic and Rare Diseases Information Center)NORD (National Organization for Rare Disorders)Find a Genetic Counselor

General Questions to Consider

Questions that may be helpful when speaking with your healthcare team

•Are there specialists or centers of excellence with experience in this condition?
•Is there a patient registry I could participate in?
•Should my family members consider genetic testing?
•What clinical trials might be available for this condition?
•Are there patient advocacy groups I should connect with?

Clinical

Associated Genes

1 gene

BAG3

Gene data from HGNC • Click to view on NCBI Gene

Inheritance Pattern

Autosomal Dominant

Inheritance patterns describe how genetic conditions are passed from parents to children.

Treatment

Support

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:621095

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AI-Generated Content: This summary was generated using AI. Always consult with qualified healthcare providers for medical guidance.

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Charcot-Marie-tooth disease, axonal, type 2JJ

Patient-Friendly Information

Overview

Symptoms & Signs

Causes & Risk Factors

Treatment & Management

Prognosis & Outlook

Research & Clinical Trials

Quick Resources

General Questions to Consider

Overview

Symptoms & Signs

Causes & Risk Factors

Treatment & Management

Prognosis & Outlook

Research & Clinical Trials

Quick Resources

General Questions to Consider

Overview

Overview

Symptoms & Signs

Causes & Risk Factors

Treatment & Management

Prognosis & Outlook

Research & Clinical Trials

Quick Resources

General Questions to Consider

Clinical

Associated Genes

Inheritance Pattern

Treatment

Support

External Resources

OMIM

Related Diseases

Know a Patient Advocacy Group for this condition?

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