An autosomal dominant nonsyndromic deafness that has material basis in variation in the chromosome region 4q12-q13.1.
Comprehensive, easy-to-understand information about this condition
How we create this content →The documentation surrounding autosomal dominant nonsyndromic hearing loss 27 is limited due to the rarity of the condition, which affects a small number of individuals worldwide. As a result, systematic clinical studies have not been extensively conducted. Additionally, the genetic basis was only recently identified, and ongoing clinical characterization is needed to fully understand the condition.
To navigate your condition effectively, consider consulting with an audiologist who specializes in hereditary hearing loss. Genetic counseling is also recommended to discuss the implications of the REST gene mutation for you and your family. While there are currently no identified patient organizations specifically for DFNA27, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information and support. Additionally, inquire about any available genetic testing options for family members.
Actionable guidance for navigating care for autosomal dominant nonsyndromic hearing loss 27
To navigate your condition effectively, consider consulting with an audiologist who specializes in hereditary hearing loss. Genetic counseling is also recommended to discuss the implications of the REST gene mutation for you and your family. While there are currently no identified patient organizations specifically for DFNA27, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information and support. Additionally, inquire about any available genetic testing options for family members.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The documentation surrounding autosomal dominant nonsyndromic hearing loss 27 is limited due to the rarity of the condition, which affects a small number of individuals worldwide. As a result, systematic clinical studies have not been extensively conducted. Additionally, the genetic basis was only recently identified, and ongoing clinical characterization is needed to fully understand the condition.
To navigate your condition effectively, consider consulting with an audiologist who specializes in hereditary hearing loss. Genetic counseling is also recommended to discuss the implications of the REST gene mutation for you and your family. While there are currently no identified patient organizations specifically for DFNA27, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information and support. Additionally, inquire about any available genetic testing options for family members.
Actionable guidance for navigating care for autosomal dominant nonsyndromic hearing loss 27
To navigate your condition effectively, consider consulting with an audiologist who specializes in hereditary hearing loss. Genetic counseling is also recommended to discuss the implications of the REST gene mutation for you and your family. While there are currently no identified patient organizations specifically for DFNA27, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information and support. Additionally, inquire about any available genetic testing options for family members.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The documentation surrounding autosomal dominant nonsyndromic hearing loss 27 is limited due to the rarity of the condition, which affects a small number of individuals worldwide. As a result, systematic clinical studies have not been extensively conducted. Additionally, the genetic basis was only recently identified, and ongoing clinical characterization is needed to fully understand the condition.
To navigate your condition effectively, consider consulting with an audiologist who specializes in hereditary hearing loss. Genetic counseling is also recommended to discuss the implications of the REST gene mutation for you and your family. While there are currently no identified patient organizations specifically for DFNA27, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information and support. Additionally, inquire about any available genetic testing options for family members.
Actionable guidance for navigating care for autosomal dominant nonsyndromic hearing loss 27
To navigate your condition effectively, consider consulting with an audiologist who specializes in hereditary hearing loss. Genetic counseling is also recommended to discuss the implications of the REST gene mutation for you and your family. While there are currently no identified patient organizations specifically for DFNA27, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information and support. Additionally, inquire about any available genetic testing options for family members.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Inheritance patterns describe how genetic conditions are passed from parents to children.
Age of onset indicates when symptoms typically first appear.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 6, 2026
Consider asking your healthcare providers these condition-specific questions
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.