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Cap polyposis (CP) is a rare colorectal disease characterized by multiple inflammatory polyps that predominantly affect the rectosigmoid area and that manifests primarily as rectal bleeding with abnormal transit, constipation and diarrhea.
Features include always present findings: Colorectal polyposis; and very common findings: Constipation, Abdominal pain, Hematochezia, and Atrophic gastritis. 8 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Digestive system | 4 | Constipation, Abdominal pain, Diarrhea |
Phenotype severity distribution: 1 always present feature, 4 very common features, 3 common features.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for cap polyposis.
13 publications have been identified in PubMed for cap polyposis. Research spans Case Report / Case Series (77%), Review / Meta-Analysis (15%), and Clinical Trial Publication (8%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 10 | 77% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 2:39 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
1 |
Weight loss |
2 |
15% |
Clinical study results | 1 | 8% |
Pellegrino R (2026). [PMID: 39629812](https://pubmed.ncbi.nlm.nih.gov/39629812/). *Revista espanola de enfermedades digestivas*. [Case Report / Case Series]
Ying CL (2026). [PMID: 41806923](https://pubmed.ncbi.nlm.nih.gov/41806923/). *Clinics and research in hepatology and gastroenterology*. [Case Report / Case Series]
Huang M (2026). [PMID: 42165178](https://pubmed.ncbi.nlm.nih.gov/42165178/). *United European Gastroenterol J*. [Case Report / Case Series]
Pham HT (2025). [PMID: 40761972](https://pubmed.ncbi.nlm.nih.gov/40761972/). *Cureus*. [Case Report / Case Series]
Gong YQ (2025). [PMID: 39078063](https://pubmed.ncbi.nlm.nih.gov/39078063/). *The American journal of gastroenterology*. [Case Report / Case Series]
Sassatelli R (2025). [PMID: 40749738](https://pubmed.ncbi.nlm.nih.gov/40749738/). *Endoscopy*. [Case Report / Case Series]
Liu X (2025). [PMID: 41031054](https://pubmed.ncbi.nlm.nih.gov/41031054/). *International journal of general medicine*. [Review / Meta-Analysis]
Coleman GT (2025). [PMID: 40330084](https://pubmed.ncbi.nlm.nih.gov/40330084/). *Case reports in gastroenterology*. [Case Report / Case Series]
Moreno Pimentel C (2025). [PMID: 38873995](https://pubmed.ncbi.nlm.nih.gov/38873995/). *Revista espanola de enfermedades digestivas*. [Case Report / Case Series]
Liu L (2024). [PMID: 38224678](https://pubmed.ncbi.nlm.nih.gov/38224678/). *Journal of gastroenterology and hepatology*. [Review / Meta-Analysis]