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Nonpapillary Renal Cell Carcinoma — NIH Grants & Funding

MONDO:0007763

Funding Landscape

Nonpapillary Renal Cell Carcinoma has active NIH research funding with 20 funded grants totaling $17.3M.

20funded grants from NIH

Portfolio: $5.9MCumulative: $17.3M12 active8 completed22 PIs18 institutions

1 new grant started in the last 12 months.

By Research Theme

Basic Science

Translational

Clinical

Epi / Nat. History

Gene/Cell Therapy

Biomarker / Dx

Funding by Fiscal Year

NIH fiscal year (Oct–Sep)

$3.9M

FY22

$3.7M

FY23

$4.5M

FY24

$4.2M

FY25

$923K

FY26

By Funding Mechanism

R01

F30

F31

K08

N43

R03

Basic Science(10)

Basic ScienceR01Active

Investigation of the role of epithelial-mesenchymal plasticity in renal cell carcinoma

Genovese, Giannicola·UNIVERSITY OF TX MD ANDERSON CAN CTR·HOUSTON, TX

$630,665 (FY2025)

NIH RePORTER

Basic ScienceZIACompleted

Interrogating genetic interactions dependencies in renal cell carcinoma

Aregger, Michael·DIVISION OF BASIC SCIENCES - NCI

$611,682 (FY2024)

NIH RePORTER

Basic ScienceK08Active

Investigating the Role of KEAP1 Germline and Somatic Mutations in Renal Cell Carcinoma

Carlo, Maria·SLOAN-KETTERING INST CAN RESEARCH·NEW YORK, NY

$266,666 (FY2025)

NIH RePORTER

Basic ScienceF30Active

The Oncogenic functions of YAP/TAZ in Renal Cell Carcinoma

McIntosh, Alec·GEORGETOWN UNIVERSITY·WASHINGTON, DC

$54,538 (FY2025)

NIH RePORTER

Basic ScienceR01Completed

The Metabolic Pathogenesis of Chromophobe Renal Cell Carcinoma

Henske, Elizabeth et al.·BRIGHAM AND WOMEN'S HOSPITAL·BOSTON, MA

$399,620 (FY2022)

NIH RePORTER

Basic ScienceR01Completed

CIRCADIAN REGULATION OF HIF2alpha IN RENAL CELL CARCINOMA

Lamia, Katja·SCRIPPS RESEARCH INSTITUTE, THE·LA JOLLA, CA

$100,451 (FY2022)

NIH RePORTER

Basic ScienceR03Completed

Pro-tumorigenic roles of a VHL isoform in Clear Cell Renal Cell Carcinoma

D'SOUZA-SCHOREY, CRISLYN·UNIVERSITY OF NOTRE DAME·NOTRE DAME, IN

$78,250 (FY2024)

NIH RePORTER

Basic ScienceF31Completed

Unraveling the influence of genetic subtype on spatial configurations of tissue and immune compartment composition in clear cell renal cell carcinoma

Nyman, Jackson·HARVARD UNIVERSITY·CAMBRIDGE, MA

$26,794 (FY2022)

NIH RePORTER

Basic ScienceF30Completed

Metabolic Contributions of Individual Cellular Compartments to the Diversity of the Tumor Microenvironment in Renal Cell Carcinoma

Reinfeld, Bradley·VANDERBILT UNIVERSITY·Nashville, TN

$26,412 (FY2023)

NIH RePORTER

Basic ScienceF31Completed

Contributions of SETD2 mutations in clear cell renal cell carcinoma (ccRCC)

Dhar, Shilpa·UT SOUTHWESTERN MEDICAL CENTER·DALLAS, TX

$19,154 (FY2024)

NIH RePORTER

Translational(6)

TranslationalR01Active

Macrophages as modulators of T cell function and therapeutic response in clear cell renal cell carcinoma

Hakimi, Abraham·SLOAN-KETTERING INST CAN RESEARCH·NEW YORK, NY

$465,743 (FY2025)

NIH RePORTER

TranslationalR01Active

The role of the RNA demethylase FTO in metabolic reprogramming of renal cell carcinoma

Rankin, Erinn·STANFORD UNIVERSITY·STANFORD, CA

$429,345 (FY2026)

NIH RePORTER

TranslationalR01Active

The role of Angiopoietin-like 4 in clear cell renal cell carcinoma and its therapeutic potential

Kolb, Ryan·UNIVERSITY OF FLORIDA·GAINESVILLE, FL

$311,966 (FY2026)

NIH RePORTER

TranslationalR21Active

Therapeutic targeting of VHL-deficient clear cell renal cell carcinoma

Razorenova, Olga·UNIVERSITY OF CALIFORNIA-IRVINE·IRVINE, CA

$209,646 (FY2025)

NIH RePORTER

TranslationalR01Completed

Epigenetic Mechanisms of Drug Resistance in Renal Cell Carcinoma

Haas, Naomi et al.·STATE UNIVERSITY OF NEW YORK AT BUFFALO·AMHERST, NY

$429,896 (FY2022)

NIH RePORTER

TranslationalR01Completed

Metabolic barriers to T cell activation in clear cell renal cell carcinoma

Rathmell, Jeffrey·VANDERBILT UNIVERSITY MEDICAL CENTER·NASHVILLE, TN

$194,628 (FY2025)

NIH RePORTER

Clinical(1)

ClinicalR01Active

Developing novel polytherapies for Non-Clear Cell Renal Cell Carcinoma

Thomas, George·OREGON HEALTH & SCIENCE UNIVERSITY·PORTLAND, OR

$182,145 (FY2026)

NIH RePORTER

Epi / Nat. History(1)

Epi / Nat. HistoryR01Active

Body composition and the obesity paradox in clear cell renal cell carcinoma

Furberg-Barnes, Anna Helena·SLOAN-KETTERING INST CAN RESEARCH·NEW YORK, NY

$587,431 (FY2023)

NIH RePORTER

Gene/Cell Therapy(1)

Gene/Cell TherapyN43Active

SBIR FY25 Concept Award: Development of engineered tRNA therapeutics for Clear Cell Renal Cell Carcinoma

Unknown PI·CLOVERLEAF BIO, INC.·NEW HAVEN, CT

$355,000 (FY2025)

NIH RePORTER

Biomarker / Dx(1)

Biomarker / DxR44Active

A PROGNOSTIC ASSAY FOR METASTATIC CLEAR CELL RENAL CELL CARCINOMA

COUGHLIN, RICHARD·LAGRANGE SCIENTIFIC, LLC·PEWEE VALLEY, KY

$538,827 (FY2025)

NIH RePORTER

Adjacent Research(8 grants)

These grants mention Nonpapillary Renal Cell Carcinoma as part of broader research but are not primarily focused on this disease. They are not included in the funding totals above.

Other(8)

OtherR01Active

Comprehensive Liquid Biomarkers to Personalize Therapy in Renal Cell Carcinoma

McKay, Rana·UNIVERSITY OF CALIFORNIA, SAN DIEGO·LA JOLLA, CA

$2,984,495 (FY2025)

NIH RePORTER

OtherR21Active

Targeting p300/CBP in renal cell carcinoma

KOLENKO, VLADIMIR·RESEARCH INST OF FOX CHASE CAN CTR·PHILADELPHIA, PA

$483,395 (FY2025)

NIH RePORTER

OtherR37Active

Defining the Role of Renal Gluconeogenesis in Renal Cell Carcinoma

Perry, Rachel·YALE UNIVERSITY·NEW HAVEN, CT

$400,213 (FY2026)

NIH RePORTER

OtherR21Active

Assessment of a recently developed boron-based HIF inhibitor as a prospective therapy for renal cell carcinoma (RCC)

Mukherji, Mridul·UNIVERSITY OF MISSOURI KANSAS CITY·KANSAS CITY, MO

$396,061 (FY2024)

NIH RePORTER

OtherR21Completed

Sensitization to RIPK1-dependent death as a strategy to enhance response of renal cell carcinoma (RCC) to immunotherapy

TING, ADRIAN·MAYO CLINIC ROCHESTER·ROCHESTER, MN

$415,000 (FY2023)

NIH RePORTER

OtherR44Completed

Advancing Next Generation CAR-T cells for Renal Cell Carcinoma

Patel, Premal·CELLINFINITY BIO, INC.·MILFORD, CT

$400,000 (FY2024)

NIH RePORTER

OtherR21Completed

Developing TCR-T cell therapy in renal cell carcinoma

Chiou, Shin-Heng et al.·RUTGERS BIOMEDICAL AND HEALTH SCIENCES·Newark, NJ

$183,494 (FY2025)

NIH RePORTER

OtherR03Completed

Elucidating the Understudied Kinase PNCK as a Prospective Drug Target in Renal Cell Carcinoma

Schurer, Stephan·UNIVERSITY OF MIAMI SCHOOL OF MEDICINE·CORAL GABLES, FL

$159,381 (FY2023)

NIH RePORTER

Top Funded Institutions

SLOAN-KETTERING INST CAN RESEARCH$1.3M

NY3 grantsCarlo, Maria, Furberg-Barnes, Anna Helena +1

UNIVERSITY OF TX MD ANDERSON CAN CTR$631K

TX1 grantGenovese, Giannicola

DIVISION OF BASIC SCIENCES - NCI$612K

1 grantAregger, Michael

LAGRANGE SCIENTIFIC, LLC$539K

KY1 grantCOUGHLIN, RICHARD

STATE UNIVERSITY OF NEW YORK AT BUFFALO$430K

NY1 grantHaas, Naomi, Hollenhorst, Peter +1

STANFORD UNIVERSITY$429K

CA1 grantRankin, Erinn

BRIGHAM AND WOMEN'S HOSPITAL$400K

MA1 grantHenske, Elizabeth, Priolo, Carmen

CLOVERLEAF BIO, INC.$355K

CT1 grant

UNIVERSITY OF FLORIDA$312K

FL1 grantKolb, Ryan

UNIVERSITY OF CALIFORNIA-IRVINE$210K

CA1 grantRazorenova, Olga

Top Principal Investigators

Genovese, Giannicola$631K

UNIVERSITY OF TX MD ANDERSON CAN CTR·1 grant

Basic Science

Aregger, Michael$612K

DIVISION OF BASIC SCIENCES - NCI·1 grant

Basic Science

Furberg-Barnes, Anna Helena$587K

SLOAN-KETTERING INST CAN RESEARCH·1 grant

Epi / Nat. History

COUGHLIN, RICHARD$539K

LAGRANGE SCIENTIFIC, LLC·1 grant

Biomarker / Dx

Hakimi, Abraham$466K

SLOAN-KETTERING INST CAN RESEARCH·1 grant

Translational

Haas, Naomi$430K

STATE UNIVERSITY OF NEW YORK AT BUFFALO·1 grant

Translational

Hollenhorst, Peter$430K

STATE UNIVERSITY OF NEW YORK AT BUFFALO·1 grant

Translational

Pili, Roberto$430K

STATE UNIVERSITY OF NEW YORK AT BUFFALO·1 grant

Translational

Rankin, Erinn$429K

STANFORD UNIVERSITY·1 grant

Translational

Henske, Elizabeth$400K

BRIGHAM AND WOMEN'S HOSPITAL·1 grant

Basic Science

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