DREDF is a national civil rights law and policy center that advocates for the rights of people with disabilities through legal advocacy, education, and public policy development.

Disability Rights Idaho advocates for the rights of individuals with disabilities in Idaho, providing legal services, information, and referrals to help them navigate their rights and access necessary support.

Disability Rights North Carolina (DRNC) advocates for the civil rights of people with disabilities in North Carolina, providing free legal assistance and resources to help them live independently and access necessary services.

Disabled Peoples' International (DPI) is a human rights organization dedicated to protecting the rights of people with disabilities and promoting their full participation in society, with active membership in over 130 countries.

ACT for Life Services is a non-profit organization that provides advocacy, planning, and trust services for individuals with physical or intellectual disabilities, ensuring they maintain government benefits and a higher quality of life.

The Dravet Syndrome Foundation supports individuals and families affected by Dravet syndrome, a severe form of epilepsy, by funding research, increasing awareness, and providing assistance.

Dreamsickle Kids Foundation provides support and resources for children and families affected by Sickle Cell Disease and other Rare Diseases in Nevada, focusing on education, advocacy, and community outreach.

The organization focuses on raising awareness and providing resources for individuals affected by Dup15q syndrome, a neurodevelopmental disorder associated with an extra copy of a portion of chromosome 15.

Duplication Cares supports families with children and adults diagnosed with 7q11.23 Duplication Syndrome and raises awareness in the medical community about this disorder.

The Dystonia Medical Research Foundation supports research and awareness for individuals affected by dystonia, providing resources and community connections for patients and families.

Dystonia UK provides support and awareness for individuals living with dystonia, offering resources such as podcasts, events, and community engagement.

The E.WE Foundation provides global resources and support for families affected by Trisomy 18 and other rare diseases, offering education, emotional care, and direct assistance.

The EA/TEF Family Support Connection provides educational resources and emotional support for families of children born with Esophageal Atresia and Tracheoesophageal Fistula (EA/TEF).

The Erdheim-Chester Disease Global Alliance provides support and resources for individuals affected by Erdheim-Chester Disease, including information on treatment options and connections to care centers.

EURORDIS-Rare Diseases Europe is a patient advocacy organization that supports individuals affected by rare diseases and promotes research and policy initiatives to improve their lives.

Easterseals provides essential services to children and adults with disabilities, older adults, veterans, and their families, focusing on support across employment, health, education, community, and transportation.

The Eating Disorders Association Inc (Qld) is a non-profit organization that provides information, support, referrals, and support group services for individuals affected by eating disorders in Queensland, Australia.

The Ehlers Danlos Society advocates for individuals affected by Ehlers-Danlos syndromes (EDS) and hypermobility spectrum disorders (HSD), providing education, support, and funding for research.

Ehlers-Danlos Support UK is a charity dedicated to supporting individuals affected by Ehlers-Danlos syndrome (EDS) and hypermobility spectrum disorders (HSD) by providing access to medical services, support groups, and resources.

Einstök börn is a support organization for children and adolescents with rare diseases or syndromes, providing various services and support to families.