A carcinoma that arises from the ovary and is characterized by the presence of large malignant cells exhibiting neuroendocrine differentiation. The prognosis is poor.
Comprehensive, easy-to-understand information about this condition
How we create this content →The limited documentation surrounding ovarian large-cell neuroendocrine carcinoma reflects its rarity, as conditions like this often affect fewer than 1 in 100,000 individuals. This extreme rarity leads to challenges in conducting systematic clinical studies and gathering comprehensive data. Additionally, the lack of identified genetic factors and well-characterized clinical features further contributes to the documentation gaps.
To navigate your diagnosis effectively, seek a medical oncologist with experience in neuroendocrine tumors, particularly those focused on ovarian cancers. Consider participating in clinical trials, as they may provide access to new treatments. You can find information about ongoing research at ClinicalTrials.gov. Additionally, while there are currently no specific patient organizations for this condition, resources like the National Organization for Rare Disorders (NORD) can offer support and information. They can be found at rarediseases.org.
There are several orphan drugs in development for ovarian large-cell neuroendocrine carcinoma, including 225Ac, an alpha-emitting radionuclide targeting the DLL3 receptor, and various bispecific monoclonal antibodies. Currently, there are two active clinical trials investigating these treatments. For more information on these trials, you can visit ClinicalTrials.gov and search for 'ovarian large-cell neuroendocrine carcinoma'. This ongoing research offers hope for better treatment options in the future.
Actionable guidance for navigating care for ovarian large-cell neuroendocrine carcinoma
To navigate your diagnosis effectively, seek a medical oncologist with experience in neuroendocrine tumors, particularly those focused on ovarian cancers. Consider participating in clinical trials, as they may provide access to new treatments. You can find information about ongoing research at ClinicalTrials.gov. Additionally, while there are currently no specific patient organizations for this condition, resources like the National Organization for Rare Disorders (NORD) can offer support and information. They can be found at rarediseases.org.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The limited documentation surrounding ovarian large-cell neuroendocrine carcinoma reflects its rarity, as conditions like this often affect fewer than 1 in 100,000 individuals. This extreme rarity leads to challenges in conducting systematic clinical studies and gathering comprehensive data. Additionally, the lack of identified genetic factors and well-characterized clinical features further contributes to the documentation gaps.
To navigate your diagnosis effectively, seek a medical oncologist with experience in neuroendocrine tumors, particularly those focused on ovarian cancers. Consider participating in clinical trials, as they may provide access to new treatments. You can find information about ongoing research at ClinicalTrials.gov. Additionally, while there are currently no specific patient organizations for this condition, resources like the National Organization for Rare Disorders (NORD) can offer support and information. They can be found at rarediseases.org.
There are several orphan drugs in development for ovarian large-cell neuroendocrine carcinoma, including 225Ac, an alpha-emitting radionuclide targeting the DLL3 receptor, and various bispecific monoclonal antibodies. Currently, there are two active clinical trials investigating these treatments. For more information on these trials, you can visit ClinicalTrials.gov and search for 'ovarian large-cell neuroendocrine carcinoma'. This ongoing research offers hope for better treatment options in the future.
Actionable guidance for navigating care for ovarian large-cell neuroendocrine carcinoma
To navigate your diagnosis effectively, seek a medical oncologist with experience in neuroendocrine tumors, particularly those focused on ovarian cancers. Consider participating in clinical trials, as they may provide access to new treatments. You can find information about ongoing research at ClinicalTrials.gov. Additionally, while there are currently no specific patient organizations for this condition, resources like the National Organization for Rare Disorders (NORD) can offer support and information. They can be found at rarediseases.org.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The limited documentation surrounding ovarian large-cell neuroendocrine carcinoma reflects its rarity, as conditions like this often affect fewer than 1 in 100,000 individuals. This extreme rarity leads to challenges in conducting systematic clinical studies and gathering comprehensive data. Additionally, the lack of identified genetic factors and well-characterized clinical features further contributes to the documentation gaps.
To navigate your diagnosis effectively, seek a medical oncologist with experience in neuroendocrine tumors, particularly those focused on ovarian cancers. Consider participating in clinical trials, as they may provide access to new treatments. You can find information about ongoing research at ClinicalTrials.gov. Additionally, while there are currently no specific patient organizations for this condition, resources like the National Organization for Rare Disorders (NORD) can offer support and information. They can be found at rarediseases.org.
There are several orphan drugs in development for ovarian large-cell neuroendocrine carcinoma, including 225Ac, an alpha-emitting radionuclide targeting the DLL3 receptor, and various bispecific monoclonal antibodies. Currently, there are two active clinical trials investigating these treatments. For more information on these trials, you can visit ClinicalTrials.gov and search for 'ovarian large-cell neuroendocrine carcinoma'. This ongoing research offers hope for better treatment options in the future.
Actionable guidance for navigating care for ovarian large-cell neuroendocrine carcinoma
To navigate your diagnosis effectively, seek a medical oncologist with experience in neuroendocrine tumors, particularly those focused on ovarian cancers. Consider participating in clinical trials, as they may provide access to new treatments. You can find information about ongoing research at ClinicalTrials.gov. Additionally, while there are currently no specific patient organizations for this condition, resources like the National Organization for Rare Disorders (NORD) can offer support and information. They can be found at rarediseases.org.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.