acrokeratosis verruciformis

Acrokeratosis verruciformis is a rare genetic skin condition characterized by a problem with how the skin forms and renews its outer layer. People with this condition develop many small, flesh-colored, wart-like bumps, primarily on the backs of the hands, inner sides of the feet, and often around the knees and elbows. This condition is inherited in an autosomal dominant manner, meaning that having a single copy of the altered gene can lead to the development of the disease. Acrokeratosis verruciformis affects the skin's keratinization process and may be noticeable from a young age, although the severity and exact appearance of the bumps can vary among individuals.

People with acrokeratosis verruciformis usually develop numerous flesh-colored, wart-like papules. These bumps are most commonly found on the backs of the hands, the inner areas of the feet, as well as the knees and elbows.

Acrokeratosis verruciformis is caused by a genetic mutation, and it follows an autosomal dominant pattern of inheritance. This means that a change in one copy of a gene is sufficient to cause the condition. The ATP2A2 gene has been identified as a known gene associated with this disorder.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.