Bartter disease type 3

Classic Bartter syndrome is a form of Bartter syndrome that generally presents with a milder clinical picture compared to its antenatal/infantile subtype. People with this condition often experience failure to thrive along with specific laboratory findings such as low potassium levels and metabolic alkalosis. In addition to these signs, blood tests may show increased levels of renin and aldosterone, and low blood pressure with reduced response to angiotensin II. This condition is recognized as part of a group of inherited kidney disorders and is sometimes referred to by various names, including Bartter syndrome type 3, classic Bartter syndrome, and adult Bartter syndrome. The information available suggests that the clinical presentation is distinct, making it important for healthcare providers to evaluate blood tests and growth patterns when considering this diagnosis.

People with Bartter disease type 3 may show signs such as failure to thrive, low blood pressure, and low blood potassium levels. Abnormal blood results, including metabolic alkalosis and increased levels of hormones like renin and aldosterone, are also noted. These symptoms can affect growth and overall energy levels.

Bartter disease type 3 is linked to changes in the CLCNKB gene, which plays an important role in the kidneys' management of salt balance. This genetic change can affect how the kidneys function, leading to the symptoms observed in people with the condition.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.