Overview

This report reflects available clinical information. Some areas may remain under active research.(7 data sources · Data coverage: Moderate)

Overview

DOCK2 deficiency, also known as immunodeficiency type 40 or IMD40, is a rare genetic condition linked to changes in the DOCK2 gene. While detailed descriptions of the condition are limited, it is recognized to affect the immune system. The information available comes primarily from genetic references and disease databases such as OMIM, Orphanet, and GARD.

Symptoms & Signs

Information about symptoms is currently limited for this condition.

Causes & Risk Factors

DOCK2 deficiency is caused by changes in the DOCK2 gene. These genetic variations are linked to the immune system problems seen in people with this condition. More detailed information about the specific mechanisms and risk factors is currently limited.

Treatment & Management

Information about treatment options and management approaches is currently limited for this condition.

Prognosis & Outlook

Information about prognosis and quality of life considerations is currently limited for this condition.

Research & Clinical Trials

Information about current research and future directions is currently limited for this condition.

Quick Resources

Helpful links for rare disease information and support

GARD (Genetic and Rare Diseases Information Center)NORD (National Organization for Rare Disorders)Find a Genetic Counselor

General Questions to Consider

Questions that may be helpful when speaking with your healthcare team

•Are there specialists or centers of excellence with experience in this condition?
•Is there a patient registry I could participate in?
•Should my family members consider genetic testing?
•What clinical trials might be available for this condition?
•Are there patient advocacy groups I should connect with?

Clinical

Associated Genes

1 gene

DOCK2

Gene data from HGNC • Click to view on NCBI Gene

Inheritance Pattern

Autosomal Recessive

Inheritance patterns describe how genetic conditions are passed from parents to children.

Treatment

Support

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:616433

Orphanet

European rare disease database

Orphanet:447737

GARD

Genetic and Rare Diseases Info Center

GARD:12653

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DOCK2 deficiency

Patient-Friendly Information

Associated Genes

Inheritance Pattern

Associated Genes

Inheritance Pattern

Overview

Overview

Symptoms & Signs

Causes & Risk Factors

Treatment & Management

Prognosis & Outlook

Research & Clinical Trials

Quick Resources

General Questions to Consider

Clinical

Associated Genes

Inheritance Pattern

Treatment

Support

External Resources

OMIM

Orphanet

GARD

Know a Patient Advocacy Group for this condition?

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DOCK2 deficiency

Patient-Friendly Information

Associated Genes

Inheritance Pattern

Associated Genes

Inheritance Pattern

Overview

Overview

Symptoms & Signs

Causes & Risk Factors

Treatment & Management

Prognosis & Outlook

Research & Clinical Trials

Quick Resources

General Questions to Consider

Clinical

Associated Genes

Inheritance Pattern

Treatment

Support

External Resources

OMIM

Orphanet

GARD

Related Diseases

Know a Patient Advocacy Group for this condition?

Need this data in your product?