Cold autoimmune hemolytic anemia comprises two types of autoimmune hemolytic anemia (AIHA) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30B0C):...
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
The limited documentation surrounding cold autoimmune hemolytic anemia is largely due to its rarity, affecting fewer than 10,000 individuals in the U.S. This low prevalence results in fewer systematic clinical studies and a lack of comprehensive data on its clinical features and genetic basis. Additionally, the overlapping symptoms with other hemolytic anemias complicate the characterization of this condition.
To navigate your care effectively, seek a hematologist with expertise in autoimmune hemolytic anemias. They can provide tailored management strategies and help monitor your condition. While there are currently no patient organizations specifically for cold AIHA, you can explore resources from the National Organization for Rare Disorders (NORD) at rarediseases.org. Additionally, consider participating in clinical trials, which may provide access to new therapies and contribute to research efforts in this area.
There are several orphan drugs designated for the treatment of cold autoimmune hemolytic anemia, including sutimlimab-jome, which is FDA-approved. Other drugs in development include fostamatinib disodium, nipocalimab, and pegcetacoplan. Currently, there are 7 active clinical trials exploring various treatment options for this condition. For more information on these trials, you can visit ClinicalTrials.gov and search for 'autoimmune hemolytic anemia, cold type'.
Actionable guidance for navigating care for autoimmune hemolytic anemia, cold type
To navigate your care effectively, seek a hematologist with expertise in autoimmune hemolytic anemias. They can provide tailored management strategies and help monitor your condition. While there are currently no patient organizations specifically for cold AIHA, you can explore resources from the National Organization for Rare Disorders (NORD) at rarediseases.org. Additionally, consider participating in clinical trials, which may provide access to new therapies and contribute to research efforts in this area.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
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