hip dysplasia, Beukes type

Hip dysplasia, Beukes type (also known as Beukes familial hip dysplasia or BFHD) is a bone disorder that mostly affects the hip joint. It is a condition in which the hip joint begins to show signs of premature wear, leading to pain and difficulty walking. This condition usually starts in childhood and can progress to severe loss of function and limited mobility by early adulthood. People with this condition experience changes in the hip joint that can be seen on X-rays. The femoral heads (the top part of the thigh bone that fits into the hip socket) appear flattened and irregular. Over time, degenerative changes including joint space narrowing, sclerosis, and the appearance of periarticular cysts develop, which are signs of osteoarthritis specific to the hip.

Common symptoms include discomfort and pain in the hip joint along with problems in walking or gait disturbances. These symptoms typically begin in childhood and worsen over time, resulting in severe functional disability and reduced mobility by early adulthood.

Hip dysplasia, Beukes type is a familial condition with a genetic component. The UFSP2 gene has been associated with the disorder, suggesting a hereditary cause. In this condition, other joints and the spine are usually not significantly affected, and overall height remains normal.

Information about treatment is currently limited for this condition.

The condition usually progresses from early symptoms in childhood to significant mobility issues by early adulthood due to degenerative changes in the hip joint. Although severe functional disability may occur, overall general health is often maintained.

Information about current research and future directions is currently limited for this condition.