Reis-Bucklers corneal dystrophy

Reis-Bucklers corneal dystrophy is a rare eye condition that affects the cornea, the clear front part of the eye. It is characterized by bilateral, symmetrical reticular opacities in the superficial central cornea, which means that both eyes show similar patterns of cloudy areas in the central part of the cornea. These changes in the cornea can lead to progressive visual impairment. The condition is also known by several other names, including granular corneal dystrophy type III. Information in this summary is based on trusted sources including the DEFINITION, OMIM, Orphanet, and GARD entries.

People with this condition typically experience a gradual loss of clear vision. The cloudy, reticular opacities in the central cornea are a hallmark of the condition and contribute to progressive visual impairment.

Reis-Bucklers corneal dystrophy has a genetic basis. It is associated with changes in the TGFBI gene. More detailed information about the underlying genetic mechanisms is not provided in the current sources.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.