Hairy Cell Leukemia variant (HCL-V) is defined as a rare and indolent form of small, mature, B-cell leukemia characterized by splenomegaly, an elevated white blood cell (WBC) count and hyper-cellular ...
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
The limited documentation surrounding hairy cell leukemia variant (HCL-V) is largely due to its rarity, which affects fewer than 5,000 people in the U.S. This extreme rarity has resulted in a lack of systematic clinical studies and comprehensive data collection. Additionally, the phenotypic overlap with other forms of leukemia can complicate accurate characterization and understanding of HCL-V. As research continues, there is hope for better insights and treatment options.
To navigate hairy cell leukemia variant (HCL-V), consider consulting with a hematologist who specializes in leukemias or rare blood disorders. This specialist can provide insights into the latest treatment options and clinical trials. Additionally, while there are currently no patient organizations specifically for HCL-V, resources like the National Organization for Rare Disorders (NORD) at rarediseases.org can offer support and information on rare diseases. Participating in clinical trials may also provide access to new therapies and contribute to the understanding of this condition.
There are currently five active clinical trials focusing on hairy cell leukemia variant (HCL-V). Two FDA-approved treatments for hairy cell leukemia, Cladribine and Pentostatin, may also be relevant for HCL-V, although their efficacy specifically in this variant is not well-established. For more information on ongoing trials, visit ClinicalTrials.gov and search for 'hairy cell leukemia variant'.
Actionable guidance for navigating care for hairy cell leukemia variant
To navigate hairy cell leukemia variant (HCL-V), consider consulting with a hematologist who specializes in leukemias or rare blood disorders. This specialist can provide insights into the latest treatment options and clinical trials. Additionally, while there are currently no patient organizations specifically for HCL-V, resources like the National Organization for Rare Disorders (NORD) at rarediseases.org can offer support and information on rare diseases. Participating in clinical trials may also provide access to new therapies and contribute to the understanding of this condition.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
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