Senior-Loken syndrome

Senior-Loken syndrome (SLSN) is a very rare condition that affects both the kidneys and the eyes. It is defined as an oculo-renal disease where kidney problems, specifically a type of chronic kidney disease known as nephronophthisis (NPHP), occur together with problems in the retina of the eye, known as retinal dystrophy. This condition is inherited in an autosomal recessive manner, meaning that a person must inherit a faulty gene from both parents to develop the syndrome. The association of kidney and eye issues means that people with this condition require careful monitoring of both systems.

People with Senior-Loken syndrome typically experience issues related to both kidney function and vision. The kidney problems come from nephronophthisis, a type of chronic kidney disease, while the retinal dystrophy can lead to changes in vision. Detailed symptom descriptions are limited in the available information.

Senior-Loken syndrome is caused by genetic changes that are inherited in an autosomal recessive pattern. This means that a child must inherit one mutated gene from each parent in order to develop the condition. Further genetic details are not provided in the available information.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.