46,XX sex reversal 4

46,XX sex reversal 4 is a rare condition where individuals with two X chromosomes may exhibit differences in the expected development of sexual characteristics. Although detailed definitions are not available, this condition is recognized in medical classifications and is sometimes noted as Sry-Negative due to the absence of the typical SRY gene found on the Y chromosome. A gene called NR5A1 is known to be associated with this condition. While the understanding of its complete impact is still developing, ongoing research hopes to clarify the natural history of the disorder and how it affects those diagnosed with it.

Information about symptoms is currently limited for this condition.

46,XX sex reversal 4 has a genetic basis. It is linked to changes in the NR5A1 gene, which plays a role in the development of sexual characteristics. The exact mechanisms by which these changes lead to the condition are still under study.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.