A disorder caused by the presence of autoantibodies directed against phospholipids, causing a hypercoaguable state, which may result in blood clots, stroke, heart attack, and in women, significant pre...
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Documentation on antiphospholipid syndrome is limited due to its complex nature and the fact that it affects a relatively small population. The variability in symptoms and the overlap with other autoimmune conditions complicate the understanding and characterization of APS, leading to gaps in comprehensive clinical data.
Key clinical features of antiphospholipid syndrome include intrauterine growth retardation (80-99%), livedo reticularis (30-79%), and various antibody positivity such as anti-beta-2-Glycoprotein I IgG and IgM (30-79%). Other symptoms may include hypercoagulability, hypertension, premature birth, ischemic strokes, and transient ischemic attacks, emphasizing the diverse manifestations of this syndrome.
To navigate your care effectively, consider consulting a rheumatologist with expertise in autoimmune disorders, particularly those familiar with antiphospholipid syndrome. Engaging in clinical trials may provide access to cutting-edge treatments; you can find opportunities at ClinicalTrials.gov. Additionally, the National Organization for Rare Disorders (NORD) offers resources and support for individuals with rare conditions. Their website is rarediseases.org, which may help connect you with further information and support networks.
Currently, there are 50 active clinical trials investigating various aspects of antiphospholipid syndrome. These trials may explore new treatment options and management strategies. For detailed information on ongoing studies, you can visit ClinicalTrials.gov and search for 'antiphospholipid syndrome'.
Actionable guidance for navigating care for antiphospholipid syndrome
To navigate your care effectively, consider consulting a rheumatologist with expertise in autoimmune disorders, particularly those familiar with antiphospholipid syndrome. Engaging in clinical trials may provide access to cutting-edge treatments; you can find opportunities at ClinicalTrials.gov. Additionally, the National Organization for Rare Disorders (NORD) offers resources and support for individuals with rare conditions. Their website is rarediseases.org, which may help connect you with further information and support networks.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.