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A nonheritable form of pseudoxanthoma elasticum (PXE), lacking the retinal and vascular stigmata associated with the inherited form of the disorder, but having skin lesions that are clinically, histologically, and ultrastructurally similar to those seen in the inherited type.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for acquired pseudoxanthoma elasticum.
9 publications have been identified in PubMed for acquired pseudoxanthoma elasticum. Research spans Case Report / Case Series (78%), Review / Meta-Analysis (11%), and Basic Science / Preclinical (11%).
Alanazi AF (2026). [PMID: 41635354](https://pubmed.ncbi.nlm.nih.gov/41635354/). *Cureus*. [Case Report / Case Series]
Le Saux O (2025). [PMID: 40882283](https://pubmed.ncbi.nlm.nih.gov/40882283/). *Annales de dermatologie et de venereologie*. [Case Report / Case Series]
Feo A (2025). [PMID: 40239167](https://pubmed.ncbi.nlm.nih.gov/40239167/). *Retina (Philadelphia, Pa.)*. [Case Report / Case Series]
Tardieu M (2025). [PMID: 40876304](https://pubmed.ncbi.nlm.nih.gov/40876304/). *Annales de dermatologie et de venereologie*. [Case Report / Case Series]
Alshehri N (2025). [PMID: 41036178](https://pubmed.ncbi.nlm.nih.gov/41036178/). *Clinical, cosmetic and investigational dermatology*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 9:38 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about acquired pseudoxanthoma elasticum
El Jalkh J (2025). [PMID: 40407483](https://pubmed.ncbi.nlm.nih.gov/40407483/). *Dermatopathology (Basel, Switzerland)*. [Case Report / Case Series]
Brampton C (2024). [PMID: 38367909](https://pubmed.ncbi.nlm.nih.gov/38367909/). *The Journal of investigative dermatology*. [Basic Science / Preclinical]
Murshidi R (2024). [PMID: 39680970](https://pubmed.ncbi.nlm.nih.gov/39680970/). *Dermatology online journal*. [Review / Meta-Analysis]
Ingrassia JP (2024). [PMID: 39644468](https://pubmed.ncbi.nlm.nih.gov/39644468/). *Dermatology online journal*. [Case Report / Case Series]