Acrofacial dysostosis Preis type is a rare condition that has been described in one patient or family. This condition involves abnormalities in the development of the hands, with a postaxial defect (an abnormality affecting the outer part) seen on the right hand and a preaxial defect (an abnormality affecting the inner part) seen on the left hand. Because only a single case has been reported, much about this condition is not well understood. The description is limited to the hand anomalies, and additional details about the overall impact of the condition are still under study.

People with this condition have been described as having differences in hand development. Specifically, a postaxial defect of the right hand and a preaxial defect of the left hand have been noted. Due to the rarity of the condition, further information about other potential signs or symptoms is limited.

Information about causes is currently limited for this condition. There are no known genes associated with acrofacial dysostosis Preis type, and the underlying factors have not been clearly defined.