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Any Cushing syndrome due to macronodular adrenal hyperplasia in which the cause of the disease is a mutation in the KDM1A gene.
Biomarker and diagnostic research for ACTH-independent macronodular adrenal hyperplasia 3 has been reported in the published literature.
No clinical trials have been registered for ACTH-independent macronodular adrenal hyperplasia 3.
10 publications have been identified in PubMed for ACTH-independent macronodular adrenal hyperplasia 3. Research spans Review / Meta-Analysis (50%), Diagnostic / Biomarker (20%), and Case Report / Case Series (20%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 5 | 50% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 8:02 PM UTC
Online Mendelian Inheritance in Man
Common questions about ACTH-independent macronodular adrenal hyperplasia 3
Testing and diagnosis research
2 |
20% |
Patient case studies | 2 | 20% |
Laboratory research | 1 | 10% |
Koukoula C (2026). [PMID: 42067271](https://pubmed.ncbi.nlm.nih.gov/42067271/). *Endocrinol Metab Clin North Am*. [Review / Meta-Analysis]
Yüksek Acınıklı K (2026). [PMID: 38084047](https://pubmed.ncbi.nlm.nih.gov/38084047/). *J Clin Res Pediatr Endocrinol*. [Case Report / Case Series]
Leszczyńska D (2026). [PMID: 41841808](https://pubmed.ncbi.nlm.nih.gov/41841808/). *Endokrynol Pol*. [Case Report / Case Series]
Bouys L (2025). [PMID: 39921449](https://pubmed.ncbi.nlm.nih.gov/39921449/). *Eur J Endocrinol*. [Diagnostic / Biomarker]
Barlas T (2025). [PMID: 40921153](https://pubmed.ncbi.nlm.nih.gov/40921153/). *Exp Clin Endocrinol Diabetes*. [Diagnostic / Biomarker]
Vaduva P (2025). [PMID: 41403049](https://pubmed.ncbi.nlm.nih.gov/41403049/). *Eur J Endocrinol*. [Basic Science / Preclinical]
Vaduva P (2024). [PMID: 39388056](https://pubmed.ncbi.nlm.nih.gov/39388056/). *Hormones (Athens)*. [Review / Meta-Analysis]
Bouys L (2024). [PMID: 39059410](https://pubmed.ncbi.nlm.nih.gov/39059410/). *Exp Clin Endocrinol Diabetes*. [Review / Meta-Analysis]
Bouys L (2024). [PMID: 38888184](https://pubmed.ncbi.nlm.nih.gov/38888184/). *J Clin Endocrinol Metab*. [Review / Meta-Analysis]
Ghanbari Boroujeni MR (2024). [PMID: 39465833](https://pubmed.ncbi.nlm.nih.gov/39465833/). *Medicine (Baltimore)*. [Review / Meta-Analysis]
AI-curated news mentioning ACTH-independent macronodular adrenal hyperplasia 3
Updated Jul 8, 2026
A new treatment for children aged 2 or older with sickle cell disease has been approved by the U.S. Food & Drug Administration. In a press release on Wednesday, the FDA announced it had approved Casgevy, the first gene therapy for children with sickle cell disease. (NewsNation) — A new treatment for children aged 2 or older with sickle cell disease has been approved by the Food & Drug Administration (FDA). In a Wednesday news release, the FDA announced it had approved Casgevy, the first gene therapy for children with the disease. “Casgevy is a gene therapy consisting of the patient’s own (autologous) hematopoietic (blood) stem cells, administered as a one-time single dose for intravenous infusion,” the release noted. “Pediatric patients as young as 2 years of age can now access a critical additional treatment option to treat these debilitating, life-threatening diseases,” Karim Mikhail, the acting director of the Center for Biologics Evaluation and Research, wrote. “These disorders carry a heavy burden for children and their families, affecting growth, development, and long-term health in profound ways,” Megha Kaushal, acting deputy director of the Office of Therapeutic Products in CBER, said in the release.