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An adenoma of the pituitary gland that produces corticotropin. The vast majority of cases are associated with Cushing disease. Clinical manifestations include truncal obesity with thin extremities, thinning of the skin, osteoporosis, and a tendency to bruise easily. Silent or hormonally non-functioning ACTH producing adenomas have also been described. They produce symptoms of a mass-related lesion.
Biomarker and diagnostic research for ACTH-producing pituitary gland adenoma has been reported in the published literature.
2 clinical trials registered, 1 recruiting. Interventions under study include drug therapy and other interventions. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.
112 publications have been identified in PubMed for ACTH-producing pituitary gland adenoma. Research spans Case Report / Case Series (38%), Basic Science / Preclinical (19%), and Clinical Trial Publication (15%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 43 | 38% |
Laboratory research | 21 | 19% |
Clinical study results | 17 | 15% |
Disease patterns and progression | 10 | 9% |
Research summaries | 9 | 8% |
Testing and diagnosis research | 8 | 7% |
New treatment approaches | 4 | 4% |
Venugopal S (2026). [PMID: 41909309](https://pubmed.ncbi.nlm.nih.gov/41909309/). *Cureus*. [Case Report / Case Series]
Torres A (2026). [PMID: 41864564](https://pubmed.ncbi.nlm.nih.gov/41864564/). *World Neurosurg*. [Clinical Trial Publication]
Inoshita N (2026). [PMID: 40900276](https://pubmed.ncbi.nlm.nih.gov/40900276/). *Brain Tumor Pathol*. [Case Report / Case Series]
Fernández SC (2026). [PMID: 42006272](https://pubmed.ncbi.nlm.nih.gov/42006272/). *Front Endocrinol (Lausanne)*. [Case Report / Case Series]
Bandeira DB (2026). [PMID: 41636967](https://pubmed.ncbi.nlm.nih.gov/41636967/). *Reviews in endocrine & metabolic disorders*. [Review / Meta-Analysis]
Yin C (2026). [PMID: 41776503](https://pubmed.ncbi.nlm.nih.gov/41776503/). *BMC Endocr Disord*. [Diagnostic / Biomarker]
Ovenden CD (2026). [PMID: 41989873](https://pubmed.ncbi.nlm.nih.gov/41989873/). *Endocr Relat Cancer*. [Review / Meta-Analysis]
Khazanchi R (2026). [PMID: 42056614](https://pubmed.ncbi.nlm.nih.gov/42056614/). *J Neurooncol*. [Epidemiology / Natural History]
Ahmed AK (2026). [PMID: 41911599](https://pubmed.ncbi.nlm.nih.gov/41911599/). *J Neurosurg Case Lessons*. [Case Report / Case Series]
Zhao X (2026). [PMID: 41528364](https://pubmed.ncbi.nlm.nih.gov/41528364/). *Neuroradiology*. [Epidemiology / Natural History]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:43 AM UTC
Common questions about ACTH-producing pituitary gland adenoma