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No clinical trials have been registered for acute megakaryoblastic leukemia in down syndrome.
19 publications have been identified in PubMed for acute megakaryoblastic leukemia in down syndrome. Research spans Case Report / Case Series (47%), Basic Science / Preclinical (26%), and Review / Meta-Analysis (11%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 9 | 47% |
Laboratory research | 5 | 26% |
Research summaries | 2 | 11% |
Other research | 1 | 5% |
Clinical study results | 1 |
Data assembled from 3 of 12 sources · Last updated Nov 4, 2026, 8:13 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about acute megakaryoblastic leukemia in down syndrome
5%
Disease patterns and progression | 1 | 5% |
Yang W (2026). [PMID: 41767736](https://pubmed.ncbi.nlm.nih.gov/41767736/). *Open Med (Wars)*. [Case Report / Case Series]
Cai C (2026). [PMID: 42144574](https://pubmed.ncbi.nlm.nih.gov/42144574/). *Cancer Med*. [Basic Science / Preclinical]
Suzuki Y (2026). [PMID: 41949996](https://pubmed.ncbi.nlm.nih.gov/41949996/). *Blood*. [Basic Science / Preclinical]
Pan F (2026). [PMID: 42147227](https://pubmed.ncbi.nlm.nih.gov/42147227/). *Front Oncol*. [Clinical Trial Publication]
Fujisawa N (2026). [PMID: 42058364](https://pubmed.ncbi.nlm.nih.gov/42058364/). *Cureus*. [Case Report / Case Series]
Munakata M (2026). [PMID: 40769884](https://pubmed.ncbi.nlm.nih.gov/40769884/). *Fukushima J Med Sci*. [Case Report / Case Series]
Yang XQ (2026). [PMID: 41888737](https://pubmed.ncbi.nlm.nih.gov/41888737/). *BMC Pediatr*. [Case Report / Case Series]
Wu K (2025). [PMID: 40789916](https://pubmed.ncbi.nlm.nih.gov/40789916/). *Leukemia*. [Basic Science / Preclinical]
Lebedeva S (2025). [PMID: 40565358](https://pubmed.ncbi.nlm.nih.gov/40565358/). *Int J Mol Sci*. [Case Report / Case Series]
Cui DD (2025). [PMID: 40962523](https://pubmed.ncbi.nlm.nih.gov/40962523/). *Zhongguo Dang Dai Er Ke Za Zhi*. [Case Report / Case Series]
AI-curated news mentioning acute megakaryoblastic leukemia in down syndrome
Updated Oct 13, 2026
New research highlights the mechanisms of megakaryopoiesis and its dysregulation in pediatric acute megakaryoblastic leukemia. Understanding these processes may lead to improved therapeutic strategies for this rare leukemia subtype.