Acute myeloid leukemia, t(3;12)(q23;p12.3) is a type of blood cancer that is defined by a specific chromosomal change. In this condition, a piece of chromosome 3 (at q23) is exchanged with a piece of chromosome 12 (at p12.3). This translocation is a cytogenetic abnormality and is noted for its association with gene fusions like ETV6/MECOM (EVI1). This chromosomal anomaly is often seen alongside other blood disorders such as myeloproliferative disorders, myelodysplastic syndromes, and other forms of acute myelogenous leukemia. The information provided is based on the DEFINITION source field.

Information about symptoms is currently limited for this condition.

This condition is caused by a genetic change where a part of chromosome 3 and a part of chromosome 12 swap places. This translocation can lead to changes in how certain genes work, including those involved in cell growth. It is associated with ETV6/MECOM (EVI1) fusions and is linked with various blood disorders. The explanation is based on the DEFINITION details.