Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Acute zonal occult outer retinopathy (AZOOR) is a rare condition that affects the eyes. People with this condition may experience a sudden onset of photopsia (the presence of perceived flashes of light) and an area of partial vision loss (a blindspot). Other symptoms may include 'whitening of vision' or blurred vision. Although anyone can be affected, the condition is most commonly diagnosed in young women (average age 36.7 years). The underlying cause of AZOOR is currently unknown; however, some researchers have proposed that infectious agents (such as viruses) or autoimmunity may play a role in the development of the condition. No treatment has been proven to improve the visual outcome of AZOOR; however, systemic corticosteroids are the most commonly used therapy.
Biomarker and diagnostic research for acute zonal occult outer retinopathy has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
1 clinical trial registered, 1 recruiting. Interventions under study include medical devices. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.
29 publications have been identified in PubMed for acute zonal occult outer retinopathy. Research spans Case Report / Case Series (48%), Review / Meta-Analysis (24%), and Epidemiology / Natural History (14%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 14 |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 2:52 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about acute zonal occult outer retinopathy
Research summaries | 7 | 24% |
Disease patterns and progression | 4 | 14% |
Other research | 2 | 7% |
Testing and diagnosis research | 2 | 7% |
Liu ZY (2026). [PMID: 41524022](https://pubmed.ncbi.nlm.nih.gov/41524022/). *Int J Ophthalmol*. [Other]
Mount GR (2026). [PMID: 32491777](https://pubmed.ncbi.nlm.nih.gov/32491777/). *Unknown Journal*. [Review / Meta-Analysis]
Coelho-Costa I (2026). [PMID: 41612300](https://pubmed.ncbi.nlm.nih.gov/41612300/). *BMC Ophthalmol*. [Case Report / Case Series]
Feo A (2026). [PMID: 41490810](https://pubmed.ncbi.nlm.nih.gov/41490810/). *Am J Ophthalmol*. [Review / Meta-Analysis]
Chen YY (2026). [PMID: 41874676](https://pubmed.ncbi.nlm.nih.gov/41874676/). *Graefes Arch Clin Exp Ophthalmol*. [Epidemiology / Natural History]
De Simone L (2026). [PMID: 41483864](https://pubmed.ncbi.nlm.nih.gov/41483864/). *Am J Ophthalmol*. [Epidemiology / Natural History]
Hartmann S (2026). [PMID: 41780542](https://pubmed.ncbi.nlm.nih.gov/41780542/). *Klin Monbl Augenheilkd*. [Other]
Hartmann S (2025). [PMID: 41330550](https://pubmed.ncbi.nlm.nih.gov/41330550/). *Klin Monbl Augenheilkd*. [Case Report / Case Series]
Merle DA (2025). [PMID: 39058998](https://pubmed.ncbi.nlm.nih.gov/39058998/). *Retin Cases Brief Rep*. [Case Report / Case Series]
Iuliano M (2025). [PMID: 40722597](https://pubmed.ncbi.nlm.nih.gov/40722597/). *Biomedicines*. [Case Report / Case Series]