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A benign neoplasm that can arise from any of the adrenal cortical layers. It can be associated with the overproduction of glucocorticoids (Cushing's syndrome), androgenic or estrogenic steroids (adrenogenital syndrome), or mineralocorticoids (Conn's syndrome). (Sternberg Diagnostic Surgical Pathology, 3rd ed.)
Biomarker and diagnostic research for adrenal cortex adenoma has been reported in the published literature.
7 clinical trials registered, 3 recruiting. Interventions under study include procedural interventions, drug therapy, and other interventions. Pipeline includes 1 PHASE4, 2 NA. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT04127552](https://clinicaltrials.gov/study/NCT04127552) |
Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 7:14 PM UTC
European rare disease database
Common questions about adrenal cortex adenoma
Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations |
— |
University of Roma La Sapienza |
RECRUITING |
[NCT06050057](https://clinicaltrials.gov/study/NCT06050057) | Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy | — | University Hospital Olomouc | UNKNOWN |
[NCT06801249](https://clinicaltrials.gov/study/NCT06801249) | Effect of Metyrapone on Cardiovascular Risk Factors in Patients With Adrenal Incidentalomas and Cushing's Syndrome | PHASE4 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | UNKNOWN |
[NCT06250699](https://clinicaltrials.gov/study/NCT06250699) | A Single Center Randomized Controlled Study on the Promotion of Rapid Recovery | NA | Zhe Meng | RECRUITING |
[NCT03474237](https://clinicaltrials.gov/study/NCT03474237) | A Prospective Cohort Study for Patients With Adrenal Diseases | — | Seoul National University Hospital | ENROLLING_BY_INVITATION |
4 publications have been identified in PubMed for adrenal cortex adenoma. Research spans Diagnostic / Biomarker (25%), Review / Meta-Analysis (25%), and Case Report / Case Series (25%).
Hu Y (2026). [PMID: 41929471](https://pubmed.ncbi.nlm.nih.gov/41929471/). *Front Cardiovasc Med*. [Case Report / Case Series]
Wei J (2026). [PMID: 41412035](https://pubmed.ncbi.nlm.nih.gov/41412035/). *Redox Biol*. [Basic Science / Preclinical]
Abd Rahman AN (2025). [PMID: 40725432](https://pubmed.ncbi.nlm.nih.gov/40725432/). *Genes (Basel)*. [Review / Meta-Analysis]
Liu ZC (2025). [PMID: 40490431](https://pubmed.ncbi.nlm.nih.gov/40490431/). *Appl Immunohistochem Mol Morphol*. [Diagnostic / Biomarker]
AI-curated news mentioning adrenal cortex adenoma
Updated May 12, 2026
A study evaluates the effectiveness of 68Ga-DOTATOC PET/CT imaging in diagnosing Carney triad spectrum tumors alongside adrenal adenomas. This research contributes to understanding the diagnostic capabilities for these rare tumors.
A case report details the incidental discovery of an adrenal adenoma in a 10-year-old girl presenting with heart failure, identified through cardiac MRI. This finding highlights the importance of advanced imaging techniques in diagnosing underlying conditions in pediatric patients.