An intestinal disorder characterized by an opening in the anal canal to the perianal skin. In the vast majority of cases there is a history of perianal abscess.
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
The limited documentation surrounding anal fistula can be frustrating for patients and their families. This condition affects a relatively small population, which makes comprehensive clinical studies challenging. Furthermore, the absence of identified genetic factors and established inheritance patterns contributes to the scarcity of detailed research. Ongoing efforts are needed to better understand this condition and improve patient care.
The clinical picture of anal fistula is primarily characterized by the presence of an anoperineal fistula, which is observed in 80-99% of cases. Patients may also experience pruritus, cellulitis, and anal pain, each affecting 30-79% of individuals. Additionally, some patients may show an increased total leukocyte count, occurring in 5-29% of cases. These symptoms can significantly impact quality of life and may require careful management.
To navigate the challenges of anal fistula, consider seeking a specialist in colorectal surgery, as they have the expertise to manage this condition effectively. Additionally, you can explore resources such as the Genetic and Rare Diseases Information Center (GARD) at https://rarediseases.info.nih.gov, which provides valuable information on rare conditions. While there are no patient organizations specifically identified for anal fistula, participating in clinical trials may also offer insights and support. If you have concerns about genetic factors, consulting with a genetic counselor could provide further clarity.
Currently, there are 42 active clinical trials focusing on anal fistula, which may offer hope for patients seeking new treatment options. These trials are exploring various approaches to manage the condition effectively. For more information on specific trials, you can visit the ClinicalTrials.gov search page at https://clinicaltrials.gov/search?cond=anal%20fistula. Participation in these trials may provide access to cutting-edge therapies and contribute to the broader understanding of the condition.
Actionable guidance for navigating care for anal fistula
To navigate the challenges of anal fistula, consider seeking a specialist in colorectal surgery, as they have the expertise to manage this condition effectively. Additionally, you can explore resources such as the Genetic and Rare Diseases Information Center (GARD) at https://rarediseases.info.nih.gov, which provides valuable information on rare conditions. While there are no patient organizations specifically identified for anal fistula, participating in clinical trials may also offer insights and support. If you have concerns about genetic factors, consulting with a genetic counselor could provide further clarity.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.