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Aortic aneurysm, familial abdominal, 1 (MONDO:0024521) is listed in the packet under the synonyms AAA1, abdominal aortic aneurysm, and aneurysm, abdominal aortic. The packet is linked to OMIM:100070 and GARD:16491. No definition text is certified in this packet. Prevalence is not certified in this packet.
The packet records one phenotype annotation but does not list it, and no GeneReviews clinical description is attached. The packet gives adult as the onset category. Specific features and their frequencies are unknown in this packet.
Data assembled from 5 of 12 sources · Last updated Nov 4, 2026, 3:00 PM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
The packet lists no causative genes. It lists three inheritance patterns: autosomal recessive, multifactorial, and autosomal dominant. The packet does not state how these patterns relate to one another or which applies in a given family, and no molecular mechanism is certified. The genetic basis is therefore not resolved by this packet.
No diagnostic methods, criteria, or GeneReviews diagnostic section are certified in this packet. Diagnostic approaches are unknown here. One listed ClinicalTrials.gov record, NCT05617326, studies screening for abdominal aortic aneurysms in general practice by ultraportable ultrasound (sponsor: Fondation Ophtalmologique Adolphe de Rothschild; status: recruiting).
The packet lists no certified foundational therapies, no GeneReviews management text, and no FDA-approved treatments, so treatment coverage is not certified in this packet. Listed trial records mention device and procedural interventions for aortic aneurysms, such as endovascular aortic repair and stent graft systems, but these records are research studies and do not establish approved therapies for this condition.
120 trials found
Natural history and prognosis information is not certified in this packet.
ClinicalTrials.gov records in the packet include studies of abdominal and related aortic aneurysms. Examples are NCT06001918, the Nectero EAST System clinical study (Phase 2, Nectero Medical, Inc., recruiting); NCT05064540, the JAGUAR trial of EVAR outcomes (Endologix, recruiting); NCT05665101, the EVAR-SE study of sac embolization for type II endoleaks (sponsor: Univ.-Prof. Dr. Dr. med. Daniela Branzan, active, not recruiting); NCT02548546, a Mayo Clinic imaging study of aortic wall properties (recruiting); and NCT07580443, a study of patient-reported quality of life after open surgery for complex abdominal aortic aneurysms (recruiting). These records concern aortic aneurysms broadly and are not specific to the familial form. Additional records can be searched on ClinicalTrials.gov.