aquagenic palmoplantar keratoderma

Aquagenic palmoplantar keratoderma is an extremely rare condition. Because few cases have been documented, detailed clinical information is limited.

The condition is characterized by a palmar eruption that occurs after brief exposure to water, leading to symptoms such as burning pain and sweating. It is observed in cystic fibrosis patients and may relate to mutations in the CFTR gene. Treatment is often not necessary, but topical treatments can be used if required.

Patients and caregivers should consider consulting a dermatologist experienced in rare skin conditions. Genetic counseling may be beneficial, particularly for those with a family history of cystic fibrosis. Connecting with rare disease registries or online patient communities can provide additional support and resources.