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atypical coarctation of aorta - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

atypical coarctation of aorta

MONDO:0015446

Also known as:Midaortic syndromecoarctation of the abdominal aortamid-aortic dysplastic syndrome

Overview

Middle aortic coarctation is a rare vascular anomaly characterized by the segmental narrowing of the abdominal and/or distal descending thoracic aorta with varying involvement of the visceral and renal arteries that commonly presents in children and young adults with early onset and refractory hypertension, abdominal angina, lower-limb claudication and that can lead to life-threatening complications associated with severe hypertension (i.e. myocardial infarction, heart failure, aortic rupture, renal insufficiency and intracranial hemorrhage). It may be due to various congenital or acquired causes, but it is most often secondary to an acquired inflammatory disease (i.e. Takayasu arteritis or giant cell arteritis).

Diagnosis

Biomarker and diagnostic research for atypical coarctation of aorta has been reported in the published literature.

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for atypical coarctation of aorta.

64 publications have been identified in PubMed for atypical coarctation of aorta. Research spans Case Report / Case Series (61%), Review / Meta-Analysis (13%), and Epidemiology / Natural History (8%).

Research Type	Count	% of Total
Patient case studies	39	61%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:51 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:1456

GARD

Genetic and Rare Diseases Info Center

GARD:18723

Questions for Your Care Team

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atypical coarctation of aorta

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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