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autoimmune hemolytic anemia, cold type (cAHA) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

autoimmune hemolytic anemia, cold type

MONDO:0016450

Also known as:cAHAcAIHAcold AIHA

Overview

Cold autoimmune hemolytic anemia comprises two types of autoimmune hemolytic anemia (AIHA) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30B0C): cold agglutinin disease (CAD), which is the more common, and paroxysmal cold hemoglobinuria (PCH).

Diagnosis

Biomarker and diagnostic research for autoimmune hemolytic anemia, cold type has been reported in the published literature.

Prognosis

Estimated prevalence: 1-9 in 100,000 (Uncommon).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for autoimmune hemolytic anemia, cold type.

40 publications have been identified in PubMed for autoimmune hemolytic anemia, cold type. Research spans Case Report / Case Series (53%), Review / Meta-Analysis (15%), and Epidemiology / Natural History (10%).

Research Type	Count	% of Total
Patient case studies	21	53%

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:45 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:228312

GARD

Genetic and Rare Diseases Info Center

GARD:20590

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
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autoimmune hemolytic anemia, cold type

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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