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A B-cell acute leukemia characterized by the presence of lymphoblasts that carry a translocation between the E2A gene on chromosome 19 and the PBX1 gene on chromosome 1. It occurs in children and less often in adults.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for B-cell acute lymphoblastic leukemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1).
3 publications have been identified in PubMed for B-cell acute lymphoblastic leukemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1). Research spans Review / Meta-Analysis (67%) and Clinical Trial Publication (33%).
Vllahu M (2025). [PMID: 40002837](https://pubmed.ncbi.nlm.nih.gov/40002837/). *Biomedicines*. [Review / Meta-Analysis]
Lejman M (2025). [PMID: 40811980](https://pubmed.ncbi.nlm.nih.gov/40811980/). *Transl Oncol*. [Review / Meta-Analysis]
Kim H (2025). [PMID: 40632342](https://pubmed.ncbi.nlm.nih.gov/40632342/). *Blood Res*. [Clinical Trial Publication]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 9:33 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about B-cell acute lymphoblastic leukemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)