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A usually unilateral, benign and well circumscribed biphasic neoplasm that arises from the breast. It usually affects middle-aged women. It is characterized by the presence of a double layer of epithelial cells that are arranged in clefts, surrounded by a cellular, monomorphic spindle cell mesenchymal component. Mitoses are rare. Necrotic changes may be present in large tumors.
Biomarker and diagnostic research for benign breast phyllodes tumor has been reported in the published literature.
No clinical trials have been registered for benign breast phyllodes tumor.
137 publications have been identified in PubMed for benign breast phyllodes tumor. Research spans Case Report / Case Series (39%), Epidemiology / Natural History (16%), and Basic Science / Preclinical (15%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 53 | 39% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:40 AM UTC
European rare disease database
Disease patterns and progression
22 |
16% |
Laboratory research | 20 | 15% |
Research summaries | 17 | 12% |
Testing and diagnosis research | 13 | 9% |
Clinical study results | 11 | 8% |
Other research | 1 | 1% |
Lee ES (2026). [PMID: 41684628](https://pubmed.ncbi.nlm.nih.gov/41684628/). *Annals of surgical treatment and research*. [Review / Meta-Analysis]
Shao Y (2026). [PMID: 41492112](https://pubmed.ncbi.nlm.nih.gov/41492112/). *Ann Surg Oncol*. [Clinical Trial Publication]
Zhou Y (2026). [PMID: 41721415](https://pubmed.ncbi.nlm.nih.gov/41721415/). *Breast Cancer Res*. [Diagnostic / Biomarker]
Gu TQ (2026). [PMID: 41918235](https://pubmed.ncbi.nlm.nih.gov/41918235/). *Clin Transl Med*. [Basic Science / Preclinical]
Grujic D (2026). [PMID: 41892015](https://pubmed.ncbi.nlm.nih.gov/41892015/). *Diseases*. [Case Report / Case Series]
Limaiem F (2026). [PMID: 31082182](https://pubmed.ncbi.nlm.nih.gov/31082182/). *Unknown Journal*. [Other]
Tsukiyama E (2026). [PMID: 42078310](https://pubmed.ncbi.nlm.nih.gov/42078310/). *Cancer Diagn Progn*. [Epidemiology / Natural History]
Holt L (2026). [PMID: 41772243](https://pubmed.ncbi.nlm.nih.gov/41772243/). *Annals of surgical oncology*. [Epidemiology / Natural History]
Langade Y (2026). [PMID: 42236687](https://pubmed.ncbi.nlm.nih.gov/42236687/). *Ann Afr Med*. [Case Report / Case Series]
Yoneda H (2026). [PMID: 41585001](https://pubmed.ncbi.nlm.nih.gov/41585001/). *Surgical case reports*. [Basic Science / Preclinical]