Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Birdshot chorioretinopathy is a posterior uveitis characterized by multiple cream-colored, hypopigmented choroidal lesions in the fundus and a strong association with HLA-A29 and clinically presenting with blurred vision, floaters, photopsia, scotoma and nyctalopia.
Features include very common findings: Vitritis, Abnormal chorioretinal morphology, Visual loss, and Abnormal choroid morphology and others; and common findings: Vitreous floaters, Attenuation of retinal blood vessels, Macular hole, and Retinal thinning on OCT and others. 26 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Eyes | 16 | Posterior uveitis, Visual impairment, Retinal pigment epithelial atrophy |
Biomarker and diagnostic research for birdshot chorioretinopathy has been reported in the published literature.
Phenotype severity distribution: 8 very common features, 12 common features.
Estimated prevalence: 1-9 in 1,000,000 (Rare).
3 clinical trials registered, 2 recruiting. Interventions under study include other interventions and procedural interventions. Research is sponsored by a mix of industry and academic institutions.
66 publications have been identified in PubMed for birdshot chorioretinopathy. Research spans Case Report / Case Series (24%), Review / Meta-Analysis (18%), and Basic Science / Preclinical (17%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 16 |
Data assembled from 6 of 12 sources · Last updated Sep 18, 2026, 3:43 AM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Muscles | 1 | Retinal pigment epithelial atrophy |
Heart and blood vessels | 1 | Ocular hypertension |
Research summaries | 12 | 18% |
Laboratory research | 11 | 17% |
Disease patterns and progression | 11 | 17% |
Testing and diagnosis research | 8 | 12% |
Clinical study results | 8 | 12% |
De Simone L (2026). [PMID: 41919587](https://pubmed.ncbi.nlm.nih.gov/41919587/). *Ocul Immunol Inflamm*. [Basic Science / Preclinical]
Bai J (2026). [PMID: 41724162](https://pubmed.ncbi.nlm.nih.gov/41724162/). *Molecular aspects of medicine*. [Review / Meta-Analysis]
Samalia PD (2026). [PMID: 41642701](https://pubmed.ncbi.nlm.nih.gov/41642701/). *Am J Ophthalmol*. [Epidemiology / Natural History]
Marchese A (2026). [PMID: 41397232](https://pubmed.ncbi.nlm.nih.gov/41397232/). *Ocular immunology and inflammation*. [Basic Science / Preclinical]
Morvey D (2026). [PMID: 41930025](https://pubmed.ncbi.nlm.nih.gov/41930025/). *Oman J Ophthalmol*. [Case Report / Case Series]
Invernizzi A (2026). [PMID: 42150663](https://pubmed.ncbi.nlm.nih.gov/42150663/). *Am J Ophthalmol*. [Diagnostic / Biomarker]
Mahmoud I (2026). [PMID: 41640909](https://pubmed.ncbi.nlm.nih.gov/41640909/). *Cureus*. [Case Report / Case Series]
Foulonneau T (2026). [PMID: 42251038](https://pubmed.ncbi.nlm.nih.gov/42251038/). *Sci Data*. [Diagnostic / Biomarker]
Vienne-Jumeau A (2026). [PMID: 41787022](https://pubmed.ncbi.nlm.nih.gov/41787022/). *Eye (London, England)*. [Epidemiology / Natural History]
Naumkinaite D (2026). [PMID: 42181395](https://pubmed.ncbi.nlm.nih.gov/42181395/). *Cureus*. [Case Report / Case Series]
AI-curated news mentioning birdshot chorioretinopathy
Updated Apr 23, 2026
A systematic review highlights the role of immune mediators in birdshot chorioretinopathy, providing insights into potential therapeutic targets. This research may inform future studies and treatment strategies for this rare eye disease.