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Features include: Scarring alopecia of scalp.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Skin | 1 | Scarring alopecia of scalp |
Biomarker and diagnostic research for central centrifugal cicatricial alopecia has been reported in the published literature.
6 clinical trials registered, 4 recruiting. Interventions under study include drug therapy, other interventions, medical devices, and biologic therapy. Pipeline includes 2 PHASE4, 2 PHASE2, 1 EARLY_PHASE1. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT07487948](https://clinicaltrials.gov/study/NCT07487948) |
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 9:02 PM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and Lichen Planopilaris |
PHASE2 |
Icahn School of Medicine at Mount Sinai |
RECRUITING |
[NCT05416333](https://clinicaltrials.gov/study/NCT05416333) | Azelaic Acid as a Novel Treatment for Central Centrifugal Cicatricial Alopecia (CCCA) | EARLY_PHASE1 | Wake Forest University Health Sciences | ACTIVE_NOT_RECRUITING |
[NCT07508488](https://clinicaltrials.gov/study/NCT07508488) | Deucravacitinib in the Treatment of Cicatricial Alopecias | PHASE2 | Icahn School of Medicine at Mount Sinai | RECRUITING |
[NCT06998433](https://clinicaltrials.gov/study/NCT06998433) | Effect of Platelet-Rich Plasma Versus Placebo in the Treatment of Central Centrifugal Cicatricial Alopecia | PHASE4 | Baylor College of Medicine | NOT_YET_RECRUITING |
[NCT04207931](https://clinicaltrials.gov/study/NCT04207931) | Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study | PHASE4 | Wake Forest University Health Sciences | RECRUITING |
77 publications have been identified in PubMed for central centrifugal cicatricial alopecia. Research spans Review / Meta-Analysis (27%), Other (22%), and Epidemiology / Natural History (19%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 21 | 27% |
Other research | 17 | 22% |
Disease patterns and progression | 15 | 19% |
Patient case studies | 6 | 8% |
Clinical study results | 6 | 8% |
Laboratory research | 6 | 8% |
Testing and diagnosis research | 4 | 5% |
New treatment approaches | 2 | 3% |
Hill MA (2026). [PMID: 41713592](https://pubmed.ncbi.nlm.nih.gov/41713592/). *J Am Acad Dermatol*. [Epidemiology / Natural History]
Ruley A (2026). [PMID: 41742458](https://pubmed.ncbi.nlm.nih.gov/41742458/). *Int J Dermatol*. [Other]
Jackson S (2026). [PMID: 41779751](https://pubmed.ncbi.nlm.nih.gov/41779751/). *J Drugs Dermatol*. [Diagnostic / Biomarker]
Larrondo J (2026). [PMID: 40976525](https://pubmed.ncbi.nlm.nih.gov/40976525/). *J Am Acad Dermatol*. [Epidemiology / Natural History]
McCarthy RL (2026). [PMID: 41801167](https://pubmed.ncbi.nlm.nih.gov/41801167/). *J Invest Dermatol*. [Review / Meta-Analysis]
Garg KS (2026). [PMID: 41779755](https://pubmed.ncbi.nlm.nih.gov/41779755/). *J Drugs Dermatol*. [Clinical Trial Publication]
Shafiei-Jahani P (2026). [PMID: 41987782](https://pubmed.ncbi.nlm.nih.gov/41987782/). *Front Med (Lausanne)*. [Review / Meta-Analysis]
Baker NJ (2026). [PMID: 41925130](https://pubmed.ncbi.nlm.nih.gov/41925130/). *J Cutan Med Surg*. [Other]
Ong MM (2026). [PMID: 41547373](https://pubmed.ncbi.nlm.nih.gov/41547373/). *J Am Acad Dermatol*. [Epidemiology / Natural History]
Tolete C (2026). [PMID: 41675020](https://pubmed.ncbi.nlm.nih.gov/41675020/). *JAAD Case Rep*. [Case Report / Case Series]