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An astrocytic tumor appearing before the age of twenty one without designation of benign or malignant nor designated location.
Biomarker and diagnostic research for childhood astrocytic tumor has been reported in the published literature.
No approved treatments are currently available for childhood astrocytic tumor. An additional 1 compound holds orphan drug designation.
While no drugs are FDA-approved specifically for childhood astrocytic tumor, some of the following designated compounds may be used off-label in clinical practice. Treatment decisions should be made in consultation with a specialist familiar with this condition.
The following drugs have received orphan drug designation from the FDA for childhood astrocytic tumor. Orphan designation reflects regulatory interest and does not indicate approval for treatment.
Brand Name | Generic Name | Sponsor |
|---|
2 clinical trials registered, 2 recruiting. Interventions under study include drug therapy, procedural interventions, and biologic therapy. Pipeline includes 2 PHASE2. Research is primarily sponsored by academic and government institutions.
82 publications have been identified in PubMed for childhood astrocytic tumor. Research spans Case Report / Case Series (30%), Basic Science / Preclinical (27%), and Epidemiology / Natural History (23%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 25 |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 4:33 PM UTC
Designated
Exclusivity End |
|---|
Designation Status |
|---|
ranagengliotucel-L | ranagengliotucel-L | NovaRx Corporation | 2009 | — | Designated |
Gene therapy approaches for childhood astrocytic tumor have been reported in the published literature.
2 trials found
Laboratory research | 22 | 27% |
Disease patterns and progression | 19 | 23% |
Testing and diagnosis research | 8 | 10% |
New treatment approaches | 4 | 5% |
Research summaries | 3 | 4% |
Clinical study results | 1 | 1% |
Cabahug VLO (2026). [PMID: 41494084](https://pubmed.ncbi.nlm.nih.gov/41494084/). *Retinal cases & brief reports*. [Case Report / Case Series]
Ngbwa GG (2026). [PMID: 41764114](https://pubmed.ncbi.nlm.nih.gov/41764114/). *Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery*. [Epidemiology / Natural History]
Jaspersen SL (2026). [PMID: 41925077](https://pubmed.ncbi.nlm.nih.gov/41925077/). *Pediatr Blood Cancer*. [Case Report / Case Series]
Sato H (2026). [PMID: 41483402](https://pubmed.ncbi.nlm.nih.gov/41483402/). *Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery*. [Basic Science / Preclinical]
Bång-Rudenstam A (2026). [PMID: 41673170](https://pubmed.ncbi.nlm.nih.gov/41673170/). *Nat Cell Biol*. [Basic Science / Preclinical]
Senyurek S (2026). [PMID: 41863652](https://pubmed.ncbi.nlm.nih.gov/41863652/). *Neurosurg Rev*. [Case Report / Case Series]
Rrapaj E (2026). [PMID: 41620461](https://pubmed.ncbi.nlm.nih.gov/41620461/). *Cell death & disease*. [Basic Science / Preclinical]
Yildirim UM (2026). [PMID: 41454823](https://pubmed.ncbi.nlm.nih.gov/41454823/). *Pediatric blood & cancer*. [Case Report / Case Series]
Autio U (2026). [PMID: 41864483](https://pubmed.ncbi.nlm.nih.gov/41864483/). *Toxicol Lett*. [Review / Meta-Analysis]
Kulac I (2026). [PMID: 41568174](https://pubmed.ncbi.nlm.nih.gov/41568174/). *Neuro-oncology advances*. [Epidemiology / Natural History]