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A high grade malignant bone-forming mesenchymal neoplasm that produces osteoid and occurs in childhood. It arises from the medullary portion of the bone. It affects the long bones, and most commonly, the distal femur, proximal tibia, and proximal humerus. Pain with or without a palpable mass is the most common clinical presentation. It usually has an aggressive growth and may metastasize through the hematogenous route. The lung is the most frequent site of metastasis.
Biomarker and diagnostic research for childhood intracortical osteosarcoma has been reported in the published literature.
No clinical trials have been registered for childhood intracortical osteosarcoma.
4 publications have been identified in PubMed for childhood intracortical osteosarcoma. Research spans Case Report / Case Series (50%), Diagnostic / Biomarker (25%), and Review / Meta-Analysis (25%).
Matcuk GR (2025). [PMID: 39718620](https://pubmed.ncbi.nlm.nih.gov/39718620/). *Skeletal radiology*. [Diagnostic / Biomarker]
Chantre-Justino M (2025). [PMID: 39810900](https://pubmed.ncbi.nlm.nih.gov/39810900/). *Biomedical reports*. [Case Report / Case Series]
Nita A (2024). [PMID: 39926959](https://pubmed.ncbi.nlm.nih.gov/39926959/). *Journal of pharmacy & bioallied sciences*. [Case Report / Case Series]
Liu R (2024). [PMID: 38539216](https://pubmed.ncbi.nlm.nih.gov/38539216/). *Journal of orthopaedic surgery and research*. [Review / Meta-Analysis]
Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 11:56 AM UTC