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An acute or chronic leukemia that occurs during childhood.
Biomarker and diagnostic research for childhood leukemia has been reported in the published literature.
30 clinical trials registered, 14 recruiting. Interventions under study include drug therapy, other interventions, biologic therapy, and gene therapy. Pipeline includes 3 PHASE3, 7 PHASE2, 7 PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT06752785](https://clinicaltrials.gov/study/NCT06752785) |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 5:31 AM UTC
Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.
Common questions about childhood leukemia
CD19/CD22 CAR-T Cell Therapy in MRD-Positive B-lineage Acute Lymphoblastic Leukemia in Children. |
PHASE1 |
Guangzhou Women and Children's Medical Center |
RECRUITING |
[NCT06764238](https://clinicaltrials.gov/study/NCT06764238) | Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol | PHASE2 | Institute of Hematology & Blood Diseases Hospital, China | RECRUITING |
[NCT03719105](https://clinicaltrials.gov/study/NCT03719105) | Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma | EARLY_PHASE1 | New York Medical College | RECRUITING |
[NCT06855810](https://clinicaltrials.gov/study/NCT06855810) | Newly-diagnosed Pediatric T-cell ALL Protocol | PHASE2 | Institute of Hematology & Blood Diseases Hospital, China | RECRUITING |
[NCT05994690](https://clinicaltrials.gov/study/NCT05994690) | CHIP-AML22/Master: An Open Label Complex Clinical Trial in Newly Diagnosed Pediatric de Novo AML Patients | PHASE3 | Princess Maxima Center for Pediatric Oncology | RECRUITING |
468 publications have been identified in PubMed for childhood leukemia. Kisho has analyzed 266 by research type. Research spans Epidemiology / Natural History (28%), Review / Meta-Analysis (22%), and Basic Science / Preclinical (19%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 74 | 28% |
Research summaries | 58 | 22% |
Laboratory research | 50 | 19% |
Clinical study results | 37 | 14% |
Testing and diagnosis research | 21 | 8% |
Patient case studies | 11 | 4% |
New treatment approaches | 11 | 4% |
Other research | 4 | 2% |
Blair HA (2026). [PMID: 41138047](https://pubmed.ncbi.nlm.nih.gov/41138047/). *Drugs*. [Review / Meta-Analysis]
Soliman HMH (2026). [PMID: 41710533](https://pubmed.ncbi.nlm.nih.gov/41710533/). *Blood and lymphatic cancer : targets and therapy*. [Review / Meta-Analysis]
Salmon C (2026). [PMID: 41224127](https://pubmed.ncbi.nlm.nih.gov/41224127/). *Environmental research*. [Epidemiology / Natural History]
Veneziano-Broccia M (2026). [PMID: 41486745](https://pubmed.ncbi.nlm.nih.gov/41486745/). *Pediatric blood & cancer*. [Epidemiology / Natural History]
Takahashi H (2026). [PMID: 40906031](https://pubmed.ncbi.nlm.nih.gov/40906031/). *International journal of hematology*. [Basic Science / Preclinical]
Núñez-Enríquez JC (2026). [PMID: 41151067](https://pubmed.ncbi.nlm.nih.gov/41151067/). *Revista medica del Instituto Mexicano del Seguro Social*. [Clinical Trial Publication]
Mimura K (2026). [PMID: 41790573](https://pubmed.ncbi.nlm.nih.gov/41790573/). *Blood*. [Clinical Trial Publication]
Vieira Martins M (2026). [PMID: 41505662](https://pubmed.ncbi.nlm.nih.gov/41505662/). *Journal of clinical oncology : official journal of the American Society of Clinical Oncology*. [Epidemiology / Natural History]
Ward MH (2026). [PMID: 41833871](https://pubmed.ncbi.nlm.nih.gov/41833871/). *Environmental research*. [Basic Science / Preclinical]
Obeagu EI (2026). [PMID: 41675902](https://pubmed.ncbi.nlm.nih.gov/41675902/). *Annals of medicine and surgery (2012)*. [Clinical Trial Publication]
AI-curated news mentioning childhood leukemia
Updated Jul 21, 2026
A comprehensive genomic analysis of five families reveals the significance of individual functional analysis for rare ETV6 germline variants in childhood leukemias. This study highlights the potential role of ETV6 mutations in the development of these cancers.