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childhood pleomorphic rhabdomyosarcoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

childhood pleomorphic rhabdomyosarcoma

MONDO:0004233

Also known as:Pleomorphic rhabdomyosarcomachildhood anaplastic rhabdomyosarcomapaediatric pleomorphic rhabdomyosarcoma

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Overview

A rare aggressive rhabdomyosarcoma occurring in children. The neoplasm is characterized by the presence of bizarre round, spindle, and polygonal cells.

Clinical Trials5 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for childhood pleomorphic rhabdomyosarcoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

5 clinical trials registered, 3 recruiting. Interventions under study include procedural interventions, other interventions, biologic therapy, and drug therapy. Pipeline includes 3 PHASE2, 1 PHASE1, 1 NA. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT07169344](https://clinicaltrials.gov/study/NCT07169344)

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:57 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 5 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	33	60%
Research summaries	7	13%
Laboratory research	5	9%
Clinical study results	4	7%
Disease patterns and progression	4	7%
Testing and diagnosis research	1	2%
New treatment approaches	1	2%

Kisho

childhood pleomorphic rhabdomyosarcoma

Overview

Diagnosis

Research Landscape

Medical References

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Clinicopathologic Study of 39 Mismatch Repair-deficient Sarcomas Demonstrates Recurrent Histologic Patterns and Supports Universal Screening of Pleomorphic Rhabdomyosarcoma, Uterine Leiomyosarcoma, and Undifferentiated and Unclassified Sarcomas.

Pleomorphic rhabdomyosarcoma, outcomes of patients with advanced disease treated with systemic agents: Retrospective study from the global pushing ultra-rare sarcomas towards hope (PUSH) consortium.

childhood pleomorphic rhabdomyosarcoma

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Clinicopathologic Study of 39 Mismatch Repair-deficient Sarcomas Demonstrates Recurrent Histologic Patterns and Supports Universal Screening of Pleomorphic Rhabdomyosarcoma, Uterine Leiomyosarcoma, and Undifferentiated and Unclassified Sarcomas.

Pleomorphic rhabdomyosarcoma, outcomes of patients with advanced disease treated with systemic agents: Retrospective study from the global pushing ultra-rare sarcomas towards hope (PUSH) consortium.