Choanal atresia (CA) is a congenital anomaly of the posterior nasal airway characterized by the obstruction of one (unilateral) or both (bilateral) choanal aperture(s), with clinical manifestations ra...
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 8, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 8, 2026
The limited documentation on choanal atresia is primarily due to its rarity, affecting fewer than 10,000 individuals in the U.S. This low prevalence restricts the number of systematic clinical studies and comprehensive data collection. Additionally, the variability in clinical presentation makes it challenging to establish a clear genetic or inheritance profile.
The clinical features of choanal atresia include nasal congestion (30-79%), chronic sinusitis (30-79%), and abnormal nasal mucus secretion (30-79%). Other associated symptoms may include cyanosis (5-29%), craniosynostosis (5-29%), and recurrent respiratory infections (5-29%). These symptoms can lead to significant challenges in breathing, particularly in newborns, and may require surgical intervention.
To navigate care for choanal atresia, consider seeking a pediatric otolaryngologist (ear, nose, and throat specialist) with experience in congenital airway anomalies. You may also benefit from connecting with a genetic counselor, especially if there are concerns about familial patterns. While there are currently no patient organizations specifically for choanal atresia, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information and support. Additionally, inquire about participation in any available clinical trials.
Currently, there are three active clinical trials investigating various aspects of choanal atresia. These trials aim to explore treatment options and management strategies for the condition. For more information on these studies, you can visit ClinicalTrials.gov and search for choanal atresia: https://clinicaltrials.gov/search?cond=choanal%20atresia.
Actionable guidance for navigating care for choanal atresia
To navigate care for choanal atresia, consider seeking a pediatric otolaryngologist (ear, nose, and throat specialist) with experience in congenital airway anomalies. You may also benefit from connecting with a genetic counselor, especially if there are concerns about familial patterns. While there are currently no patient organizations specifically for choanal atresia, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information and support. Additionally, inquire about participation in any available clinical trials.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 8, 2026
Consider asking your healthcare providers these condition-specific questions
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
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