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congenital high airway obstruction syndrome (CHAOS) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

congenital high airway obstruction syndrome

MONDO:1060125

Also known as:CHAOS

Overview

A rare, life-threatening fetal condition resulting complete or partial obstruction of the fetal upper airways. Laryngeal atresia is the most frequent cause, but other etiologies, such as laryngeal cyst, subglottic stenosis or atresia, tracheal atresia, and laryngeal or tracheal agenesis are also included.

Diagnosis

Biomarker and diagnostic research for congenital high airway obstruction syndrome has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for congenital high airway obstruction syndrome.

11 publications have been identified in PubMed for congenital high airway obstruction syndrome. Research spans Case Report / Case Series (55%), Review / Meta-Analysis (27%), and Other (9%).

Research Type	Count	% of Total
Patient case studies	6	55%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:44 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:700286

Questions for Your Care Team

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congenital high airway obstruction syndrome

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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