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A congenital abnormality characterized by the presence of a continuous layer of skin extending over the eyeballs and the absence of eyelids and the palpebral fissure.
No clinical trials have been registered for cryptophthalmia.
10 publications have been identified in PubMed for cryptophthalmia. Research spans Case Report / Case Series (56%), Review / Meta-Analysis (22%), and Basic Science / Preclinical (22%).
Suárez LVB (2026). [PMID: 42106715](https://pubmed.ncbi.nlm.nih.gov/42106715/). *BMC Ophthalmol*. [Review / Meta-Analysis]
Barrantes Murillo DF (2026). [PMID: 41762325](https://pubmed.ncbi.nlm.nih.gov/41762325/). *Vet Res Commun*. [Case Report / Case Series]
Wei W (2025). [PMID: 41426592](https://pubmed.ncbi.nlm.nih.gov/41426592/). *Front Med (Lausanne)*. [Case Report / Case Series]
Simikyan RG (2025). [PMID: 41006360](https://pubmed.ncbi.nlm.nih.gov/41006360/). *Sci Rep*. [Basic Science / Preclinical]
Thi Pham XT (2025). [PMID: 40647604](https://pubmed.ncbi.nlm.nih.gov/40647604/). *Diagnostics (Basel)*. [Case Report / Case Series]
Simikyan RG (2025). [PMID: 39554083](https://pubmed.ncbi.nlm.nih.gov/39554083/). *bioRxiv*. [Basic Science / Preclinical]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 12:11 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Rana S (2025). [PMID: 41399579](https://pubmed.ncbi.nlm.nih.gov/41399579/). *Cureus*. [Case Report / Case Series]
Liang B (2024). [PMID: 39106617](https://pubmed.ncbi.nlm.nih.gov/39106617/). *Eur J Obstet Gynecol Reprod Biol*. [Review / Meta-Analysis]
Chen H (2024). [PMID: 38684310](https://pubmed.ncbi.nlm.nih.gov/38684310/). *Zhonghua Yi Xue Yi Chuan Xue Za Zhi*. [Case Report / Case Series]