Question 1

What is Curly hair - acral keratoderma - caries syndrome?

Accepted Answer

Curly hair - acral keratoderma - caries syndrome is an extremely rare ectodermal dysplasia syndrome. People with this condition often experience premature loss of curly, brittle, dry hair and early loss of teeth due to caries. They may also have nail dystrophy with thickened finger- and toe-nails, acral keratoderma, and reduced sweating (hypohidrosis).

Additional features include sparse eyebrows and eyelashes, a receding frontal hairline, and a flattened malar region. The severity of these features appears to increase with age.

Question 2

What are the symptoms of Curly hair - acral keratoderma - caries syndrome?

Accepted Answer

Common symptoms and signs include brittle, dry, and curly hair that is lost early, premature dental caries leading to early tooth loss, thickened and dystrophic finger- and toe-nails, and rough skin on the hands and feet (acral keratoderma). People with this condition may also have hypohidrosis (reduced sweating), sparse eyebrows and eyelashes, a receding frontal hairline, and a flattened facial profile in the cheek area (malar region).

Question 3

What causes Curly hair - acral keratoderma - caries syndrome?

Accepted Answer

Information about causes is currently limited for this condition.

Question 4

How rare is Curly hair - acral keratoderma - caries syndrome?

Accepted Answer

Curly hair - acral keratoderma - caries syndrome is classified as very rare. The estimated prevalence is approximately <1 in 1,000,000. Because rare disease data can be limited, actual numbers may differ from published estimates.

Question 5

How is Curly hair - acral keratoderma - caries syndrome diagnosed?

Accepted Answer

Information about diagnosis is currently limited for this condition.

Question 6

Are there treatments for Curly hair - acral keratoderma - caries syndrome?

Accepted Answer

Information about treatment is currently limited for this condition.

Question 7

What complications can arise from Curly hair - acral keratoderma - caries syndrome?

Accepted Answer

People with Curly hair - acral keratoderma - caries syndrome may face several complications as they age. These can include worsening symptoms like more severe hair loss, increased dental issues leading to tooth loss, and worsening skin conditions. It's important to monitor these symptoms with healthcare providers to manage complications effectively.

Question 8

How does Curly hair - acral keratoderma - caries syndrome affect daily life?

Accepted Answer

Daily life for someone with Curly hair - acral keratoderma - caries syndrome can be challenging. The condition can lead to early tooth loss, which may require dental care and adjustments in diet. Additionally, the brittle hair and skin issues can affect self-esteem and social interactions, making support from family and friends very important.

Question 9

What is the life expectancy for someone with Curly hair - acral keratoderma - caries syndrome?

Accepted Answer

Currently, there is limited information on the life expectancy of individuals with Curly hair - acral keratoderma - caries syndrome. The severity of symptoms can vary, and while some features may worsen with age, it is not clear how this affects overall life expectancy. Regular medical care and monitoring can help manage symptoms effectively.

Question 10

Are there any specialists recommended for managing Curly hair - acral keratoderma - caries syndrome?

Accepted Answer

For managing Curly hair - acral keratoderma - caries syndrome, it is beneficial to consult with specialists such as dermatologists and dentists. Dermatologists can help with skin and hair issues, while dentists can provide care for dental problems related to early tooth loss. Coordinated care from these specialists can improve quality of life.

Research Type	Count	% of Total
Patient case studies	4	36%

Kisho

Curly hair - acral keratoderma - caries syndrome

Overview

Prognosis

Research Landscape

Medical References

External Resources

OMIM

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

FAQ

Frequently Asked Questions

Recent Publications

Curly hair - acral keratoderma - caries syndrome

Overview

Prognosis

Research Landscape

Medical References

External Resources

OMIM

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

FAQ

Frequently Asked Questions

What is Curly hair - acral keratoderma - caries syndrome?

What are the symptoms of Curly hair - acral keratoderma - caries syndrome?

What causes Curly hair - acral keratoderma - caries syndrome?

How rare is Curly hair - acral keratoderma - caries syndrome?

How is Curly hair - acral keratoderma - caries syndrome diagnosed?

Are there treatments for Curly hair - acral keratoderma - caries syndrome?

What complications can arise from Curly hair - acral keratoderma - caries syndrome?

How does Curly hair - acral keratoderma - caries syndrome affect daily life?

What is the life expectancy for someone with Curly hair - acral keratoderma - caries syndrome?

Are there any specialists recommended for managing Curly hair - acral keratoderma - caries syndrome?

Recent Publications