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dermo-odonto dysplasia - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

dermo-odonto dysplasia

MONDO:0007449

Also known as:DERMOODONTODYSPLASIAdermo odontodysplasiadermoodonto dysplasia

Overview

Dermo-odonto dysplasia belongs to the group of tricho-odonto-onychial dysplasias. It is characterized by signs of variable severity: dry and thin skin, dental anomalies, nail alteration and trichodysplasia. Fourteen cases have been described so far. Autosomal dominant transmission is likely.

GeneticsAutosomal dominant

Clinical Presentation

Features include always present findings: Trichodysplasia, Nail dysplasia, and Ectodermal dysplasia. 6 total HPO annotations.

Organ System	Phenotype Count	Example Features
Skin	3	Nail dysplasia, Dry skin, Thin skin

Explore clinical features

Diagnosis

Biomarker and diagnostic research for dermo-odonto dysplasia has been reported in the published literature.

Prognosis

Phenotype severity distribution: 3 always present features.

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for dermo-odonto dysplasia.

201 publications have been identified in PubMed for dermo-odonto dysplasia. Kisho has analyzed 116 by research type. Research spans Review / Meta-Analysis (48%), Epidemiology / Natural History (20%), and Basic Science / Preclinical (12%).

Research Type	Count	% of Total
Research summaries	56	48%

Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 3:31 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:125640

Orphanet

European rare disease database

Orphanet:1660

GARD

Genetic and Rare Diseases Info Center

GARD:1816

Questions for Your Care Team

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dermo-odonto dysplasia

Overview

Clinical Presentation

Explore clinical features

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

OMIM

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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