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A rare idiopathic interstitial pneumonia characterized by accumulation of macrophages in alveolar spaces and interstitial inflammation. It usually occurs in smokers. Some patients develop progressive interstitial lung fibrosis.
Features include: Desquamative interstitial pneumonitis, Tubulointerstitial fibrosis, Respiratory distress, and Type II pneumocyte hypertrophy and 8 more.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Lungs and breathing | 5 | Desquamative interstitial pneumonitis, Respiratory distress, Type II pneumocyte hypertrophy |
Biomarker and diagnostic research for desquamative interstitial pneumonia has been reported in the published literature.
No clinical trials have been registered for desquamative interstitial pneumonia.
23 publications have been identified in PubMed for desquamative interstitial pneumonia. Research spans Review / Meta-Analysis (48%), Case Report / Case Series (30%), and Diagnostic / Biomarker (9%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 11 | 48% |
Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 11:11 AM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Kidneys and urinary system
1 |
Tubulointerstitial fibrosis |
Growth and development | 1 | Failure to thrive |
Metabolism | 1 | Abnormality of metabolism/homeostasis |
Blood and immune system | 1 | Recurrent upper respiratory tract infections |
Age of onset: infancy.
Patient case studies
7 |
30% |
Testing and diagnosis research | 2 | 9% |
Disease patterns and progression | 2 | 9% |
Other research | 1 | 4% |
Moore AE (2026). [PMID: 41513511](https://pubmed.ncbi.nlm.nih.gov/41513511/). *Semin Roentgenol*. [Review / Meta-Analysis]
Gudi H (2026). [PMID: 41521085](https://pubmed.ncbi.nlm.nih.gov/41521085/). *Semin Roentgenol*. [Review / Meta-Analysis]
Mo L (2026). [PMID: 41735806](https://pubmed.ncbi.nlm.nih.gov/41735806/). *Intern Med J*. [Other]
Alarcon-Calderon A (2026). [PMID: 41916427](https://pubmed.ncbi.nlm.nih.gov/41916427/). *Semin Respir Crit Care Med*. [Review / Meta-Analysis]
Kim MS (2026). [PMID: 41733469](https://pubmed.ncbi.nlm.nih.gov/41733469/). *Radiology*. [Diagnostic / Biomarker]
Brar N (2026). [PMID: 41728051](https://pubmed.ncbi.nlm.nih.gov/41728051/). *Clin Med Insights Case Rep*. [Case Report / Case Series]
Peng S (2025). [PMID: 40837109](https://pubmed.ncbi.nlm.nih.gov/40837109/). *Int J Chron Obstruct Pulmon Dis*. [Case Report / Case Series]
Arenas-Jiménez JJ (2025). [PMID: 40963007](https://pubmed.ncbi.nlm.nih.gov/40963007/). *Insights Imaging*. [Review / Meta-Analysis]
Kang HK (2025). [PMID: 40081337](https://pubmed.ncbi.nlm.nih.gov/40081337/). *Tuberc Respir Dis (Seoul)*. [Review / Meta-Analysis]
Sharma A (2025). [PMID: 41296291](https://pubmed.ncbi.nlm.nih.gov/41296291/). *J Assoc Physicians India*. [Case Report / Case Series]
AI-curated news mentioning desquamative interstitial pneumonia
Updated May 12, 2026
A recent case report details a patient with interstitial pneumonia associated with a primary pulmonary atypical carcinoid tumor and multiple brain metastases. This study contributes to the understanding of the complex interplay between these conditions.
A study published in PubMed examines the clinical characteristics of 20 lung adenocarcinoma patients who were misdiagnosed with interstitial pneumonia. This research highlights the diagnostic challenges and the need for improved differentiation between these conditions.
A case study highlights hepatopulmonary syndrome linked to metabolic dysfunction-associated steatotic liver disease in a patient suffering from interstitial pneumonia and COPD. This research contributes to understanding the complex interplay between these conditions.