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Congenitally uncorrected transposition of the great arteries (congenitally uncorrected TGA), also referred to as complete transposition, is a congenital cardiac malformation characterized by atrioventricular concordance and ventriculoarterial (VA) discordance.
Biomarker and diagnostic research for dextro-looped transposition of the great arteries has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
2 clinical trials registered, 2 recruiting. Interventions under study include drug therapy and other interventions. Research is primarily sponsored by academic and government institutions.
11 publications have been identified in PubMed for dextro-looped transposition of the great arteries. Research spans Case Report / Case Series (64%), Review / Meta-Analysis (18%), and Diagnostic / Biomarker (9%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 7 |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:17 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries | 2 | 18% |
Testing and diagnosis research | 1 | 9% |
Laboratory research | 1 | 9% |
Goto K (2026). [PMID: 41767025](https://pubmed.ncbi.nlm.nih.gov/41767025/). *CJC pediatric and congenital heart disease*. [Case Report / Case Series]
Volpi J (2026). [PMID: 40796658](https://pubmed.ncbi.nlm.nih.gov/40796658/). *Eur J Hum Genet*. [Basic Science / Preclinical]
Ma W (2026). [PMID: 41783016](https://pubmed.ncbi.nlm.nih.gov/41783016/). *Front Cardiovasc Med*. [Review / Meta-Analysis]
Chavhan AR (2026). [PMID: 41804411](https://pubmed.ncbi.nlm.nih.gov/41804411/). *Cureus*. [Case Report / Case Series]
Lin X (2026). [PMID: 42006588](https://pubmed.ncbi.nlm.nih.gov/42006588/). *Eur Heart J Case Rep*. [Case Report / Case Series]
Alomrani A (2025). [PMID: 40336940](https://pubmed.ncbi.nlm.nih.gov/40336940/). *Eur Heart J Case Rep*. [Case Report / Case Series]
Aldolly A (2025). [PMID: 40340415](https://pubmed.ncbi.nlm.nih.gov/40340415/). *J Investig Med High Impact Case Rep*. [Case Report / Case Series]
Hunt S (2025). [PMID: 41099374](https://pubmed.ncbi.nlm.nih.gov/41099374/). *Cardiol Young*. [Case Report / Case Series]
Zubrzycki M (2024). [PMID: 39200964](https://pubmed.ncbi.nlm.nih.gov/39200964/). *J Clin Med*. [Review / Meta-Analysis]
Young K (2024). [PMID: 38613605](https://pubmed.ncbi.nlm.nih.gov/38613605/). *The international journal of cardiovascular imaging*. [Diagnostic / Biomarker]
AI-curated news mentioning dextro-looped transposition of the great arteries
Updated Jul 29, 2026
A new study explores the developmental and genetic mechanisms underlying d-transposition of the great arteries (d-TGA) and congenitally corrected transposition of the great arteries (ccTGA). The research provides insights into the outflow tract development and its implications for these congenital heart defects.